Masthash

#DNA

Snowshadow
12 hours ago

UK Biobank releases half a million whole-genome sequences for biomedical research
The release more than doubles the size of an earlier data set and will help reveal new links between DNA, health, and disease, geneticists say

#genetics #biomedical #biology #science #news #uk #research #dna #health

https://www.science.org/content/article/uk-biobank-releases-half-million-whole-genome-sequences-biomedical-research

DigitalDreamscape
13 hours ago

The Molecule of Life
This image shows a pair of hands holding a glowing molecule that resembles DNA, the molecule of life. The molecule is composed of pink and blue spheres that represent the four bases of DNA: adenine, thymine, cytosine, and guanine. The white lines that connect the spheres are the sugar-phosphate backbone that holds the DNA strands together. #life #DNA #science #art
https://ko-fi.com/s/1e965867eb

CellBioNews
13 hours ago

Two methods for demonstrating how #photolyase isolates use light to repair damaged #DNA.

#DNA_repair #crytallography

https://phys.org/news/2023-12-methods-photolyase-isolates-dna.html

Futuro Prossimo :verified:
16 hours ago

Il sequenziamento del genoma dei neonati potrebbe presto rilevare in anticipo centinaia di malattie anche rare, stravolgendo modelli di cura e prevenzione. Questa evoluzione, che muoverà i primi passi "ufficiali" dal 2025, apre nuovi orizzonti nella medicina predittiva ma solleva anche questioni etiche e sociali.

#genetica #genomica #salute #neonati #medicina #dna #prevenzione #gattaca

https://www.futuroprossimo.it/2023/12/addio-test-neonatale-i-bambini-nasceranno-col-futuro-genetico-gia-scritto/

"Y-chromosome results highlight a significant genetic differentiation between the North-Western and South-Eastern part of the Mediterranean, the Italian Peninsula occupying an intermediate position therein. In particular, Sicily and Southern Italy reveal a shared paternal genetic background with the Balkan Peninsula and the time estimates of main Y-chromosome lineages signal paternal genetic traces of Neolithic and post-Neolithic migration events."

Sarno S, Boattini A, Carta M, Ferri G, Alù M, et al. (2014) An Ancient Mediterranean Melting Pot: Investigating the Uniparental Genetic Structure and Population History of Sicily and Southern Italy. PLOS ONE 9(4): e96074. https://doi.org/10.1371/journal.pone.0096074 #OpenAccess #OA #Research #Article #Science #STEM #Population #Genetics #PopulationGenetics #Italy #Sicily #DNA #Paleogenetics #Europe #Anthropology #Biology #Academia @science @biology @anthropology

Figure 3. Spatial Principal Component Analysis (sPCA) based on mtDNA haplogroups frequencies.

The first two global components sPC1 (a) and sPC2 (b) are depicted. Positive values are represented by black squares; negative values are represented by white squares; the size of the square is proportional to the absolute value of sPC scores.

https://doi.org/10.1371/journal.pone.0096074.g003

“The site of the hospital of St John the Evangelist was excavated in 2010, uncovering hundreds of unidentified graves. For the new study, experts in #DNA and isotope analysis, human skeletal variation and a range of other disciplines examined up to 50 individual characteristics of each skeleton, to build what they believe is one of the richest such datasets ever compiled for medieval #England."

#archeology #health #healthcare #Cambridge #MedievalHistory #research #humans
https://www.theguardian.com/science/2023/dec/01/archaeologists-life-stories-medieval-cambridge

G4Media 📰
2 days ago

Europarlamentarul #USR (#UniuneaSalvațiRomânia) #VladGheorghe îl critică dur pe Cătălin #Drulă în cazul dosarului vaccinurilor: „Să trimiți scrisorele la #Bruxelles să te plângi de #DNA, după ce ai fost singurul partid care s-a opus măcelului din justiție de la OUG13 încoace?.
#Drulă trebuie să înceteze acum”.

🔗 https://g4media.ro/europarlamentarul-usr-vlad-gheorghe-il-critica-dur-pe-catalin-drula-in-cazul-dosarului-vaccinurilor-sa-trimiti-scrisorele-la-bruxelles-sa-te-plangi-de-dna-dupa-ce-ai-fost-singurul-partid-care-s-a.html

#Știri #Belgia #Flandra #România #UE #UniuneaEuropeană #Europa #ParlamentulEuropean

John Carlsen
2 days ago

#SunnyvaleDPS use #DNA to solve 1979 #Sunnyvale #ColdCase #homicide of 18-year-old Estella Elena Mena

Erika Towne & Press Release POSTED 03:00 AM, November 24, 2023

https://www.svvoice.com/1979-sunnyvale-cold-case-homicide-solved/

#SiliconValleyVoice

TAO
3 days ago

If we map L to Guanine, A to Adenine, S to Cytosine, and T to Thymine, we could encode the Y-combinator directly in #DNA as:

GA GACTATT GACTATT

simplified:

GA GATT GACTATT

GATT being our omega-replicator.

Is that awesome or what?

#lambda #calculus #lambdacalculus #minimal #encoding #replication #omega #simplicity #biology #computing #computerscience #biocomputing #awesome

OddOpinions5
3 days ago
Biziday 📰
4 days ago

#Senat‎ul a votat ridicarea imunității senatorului Florin #Cîțu, fost prim-ministru, cercetat de #DNA în dosarul privind achiziția de vaccinuri anti-🦠#COVID, în timpul pandemiei.

🔗 https://biziday.ro/269031-2

#Știri #România #Sănătate

TAO
4 days ago

In this open-access paper researchers describe a #DNA system computationally equivalent to a pushdown automaton.

#DNA #computing #computerscience #nanoscale

https://www.nature.com/articles/s41598-023-35720-5

TAO
4 days ago

Researchers designed some kind of a state machine on top of DNA.

#dna #dnacomputing #nanomachines #computing

https://www.nature.com/articles/s42256-023-00707-4

TAO
4 days ago

Apparently general-purpose #DNA #computing is not a complete abstraction, and there is active work in this area. E.g.:
https://www.nature.com/articles/s41586-023-06484-9

TAO
4 days ago

https://xtao.org/last.html

LAST is an extremely minimal programming language which uses only 4 symbols (conventionally L, A, S, and T) to encode any algorithm. In that LAST is analogous with DNA, the language of biology, which uses only 4 symbols (conventionally C, G, A, and T) to encode any organism.

#last #programming #language #lambdacalculus #dna #extreme #minimal #programminglanguage

G4Media 📰
4 days ago

O secție de Poliție este construită pe unul dintre terenurile care ar fi fost obținute ilegal în dosarul fraudelor cu terenuri din Capitală.
#DNA: „Se plătește chirie și în prezent unuia dintre inculpați”.
Trei persoane reținute.

🔗 https://g4media.ro/o-sectie-de-politie-este-construita-pe-unul-dintre-terenurile-care-ar-fi-fost-obtinute-ilegal-in-dosarul-fraudelor-cu-terenuri-din-capitala-dna-se-plateste-chirie-si-in-prezent-unuia-dintr.html

#Știri #România

Manni_P :mastolove:
4 days ago

@maxplanckgesellschaft

https://mpg.de/21173804/interview-marotzke-klimakommunikation #Klima #Klimawandel #Golfstrom #WissKomm @MPI_Meteo
#Epigenetics is focused on the study of how experience changes an individual’s #genetic expression, previously considered inalterable. ... #research indicates that epigenetics is #revolutionizing the #study of #mental #health and challenging the belief that #DNA is #destiny.

#letztegeneration #history #fairytales #lug #betrug #COP28 #fossilterror #followthemoney #hemp #Janov #fridaysforfuture

Lieber @hart oh, da stößt Du jetzt eine gute #Debatte an, finde ich. Sei mir nicht böse, wenn ich nicht sofort umfassend darauf eingehe. Zur #Zeit gibt es sehr #interessante #Entwicklungen und ich möchte auch niemanden überfordern. Wenn Du magst führen wir diese Debatte so, als wäre es eine #Gerichtsverhandlung vor dem #Menschenrechtsgerichtshof [#Bundesverfassungsgericht] 
Wir würden #nachweisen, welcher #Schaden durch die #Prohibition entstanden ist und #Politikerinnen unter Eid befragen. #fff
{Seit über 10.000 Jahren nutzen die Menschen #Cannabis – Wie kommt es also, dass die älteste und vielfältigste aller #Kulturpflanzen vom Markt verschwinden konnte und  weltweit nur noch als Droge bekannt ist?

Aus #Hanf können über 40 000 verschiedene #Produkte für alle Bereiche des täglichen Lebens hergestellt werden und es  gibt verschiedene Theorien, warum der #Rohstoff Hanf verschwand.} 

#Weedmob #Wissen #Kenne die #OffshoreIndustrie #Geldwäsche #global #Investoren #netzfrauen #fff #Mafia
Wer sich tiefer und intensiver [z.B. für Plädoyer vor einem hohen Gericht] informieren und vorbereiten möchte, oder Interesse hat, der kann sich auf Janovs Webseite sachkundig machen, insbesondere über den neuesten Stand der #Biowissenschaften [Epigenetik und {Suchtverhalten wegen} #Traumata durch Endokrine Disruptoren] [siehe #Monsanto und Co.]. Ich rate dringend die Verursacher zu verklagen. #LikeMonsanto 
https://cigognenews.blogspot.com/search?q=addiction
Wissen zu Epigenetik #antipro weiß mehr! https://cigognenews.blogspot.com/searc
GW
4 days ago

Reverence For #Genius The Perfect Words To Describe How #Musicians, #Guitarists, and Fans, Including This #Writer, Have Felt About Ry Cooder

“With Ry, man, he can just play one note on the slide and it just melts.” That’s all I have to say about it. It’s amazing. He made a ton of soundtracks in addition to his many records, and all of them is fantastic. He’s such a musicologist that music and guitar appear to be written all over his #DNA. I can’t help but be inspired”

https://medium.com/@BluesBeat/reverence-the-perfect-word-to-describe-how-musicians-guitarists-and-fans-including-this-writer-37003c141ec0

Ry Cooder
G4Media 📰
4 days ago

Dosarul vaccinurilor: Solicitarea #DNA pentru începerea urmăririi penale față de Florin #Cîțu, la vot în Plenul #Senat‎ului.
Fostul premier își îndeamnă colegii să voteze pentru ridicarea imunității.

🔗 https://g4media.ro/dosarul-vaccinurilor-solicitarea-dna-pentru-inceperea-urmaririi-penale-fata-de-florin-citu-la-vot-in-plenul-senatului-fostul-premier-isi-indeamna-colegii-sa-voteze-pentru-ridicarea-imunitatii.html

#Știri #România

G4Media 📰
5 days ago
G4Media 📰
5 days ago

Cine este procuroarea Mihaiela Iorga #Moraru, propusă de ministra justiției Alina #Gorghiu pentru șefia secției de combatere a corupției din #DNA.

🔗 https://g4media.ro/procuroarea-mihaiela-iorga-moraru-propusa-de-ministra-justitiei-alina-gorghiu-pentru-sefia-sectiei-de-combatere-a-coruptiei-din-dna.html

#Știri #România

G4Media 📰
5 days ago

My sister and neice. I did not know them till 2 years ago, but making up for 70 years not knowing!!. #DNA! #Great #day!!

G4Media 📰
5 days ago

”Hoția imobiliară din Parcului Herăstrău era vizibilă pentru toți”.
#ClotildeArmand, despre ancheta #DNA cu fraude de terenuri în cea mai scumpă zonă a Capitalei.

🔗 https://g4media.ro/hotia-imobiliara-din-parcului-herastrau-era-vizibila-pentru-toti-clotilde-armand-despre-ancheta-dna-cu-fraude-de-terenuri-in-cea-mai-scumpa-zona-a-capitalei.html

#Știri #România

G4Media 📰
5 days ago

Vor fi vândute două autoturisme de lux confiscate de la ofițerii de la Permise #Suceava.
Procurorii #DNA au cerut asta pentru ca autoturismele să nu-și piardă valoarea.

🔗 https://g4media.ro/vor-fi-vandute-doua-autoturisme-de-lux-confiscate-de-la-ofiterii-de-la-permise-suceava-procurorii-dna-au-cerut-asta-pentru-ca-autoturismele-sa-nu-si-piarda-valoarea.html

#Știri #România

G4Media 📰
5 days ago

Percheziții #DNA într-un dosar care vizează fraude cu terenuri în cea mai scumpă zonă a Capitalei.
Prejudiciu estimat la peste 10 milioane 💶#EUR.
SURSE: Pe majoritatea terenurilor au fost construite ansambluri rezidențiale.

🔗 https://g4media.ro/perchezitii-dna-intr-un-dosar-care-vizeaza-fraude-cu-terenuri-in-cea-mai-scumpa-zona-a-capitalei-prejudiciu-estimat-la-peste-10-milioane-de-euro-surse-pe-majoritatea-terenurilor-au-fost-construit.html

#Știri #România

Laborjournal
5 days ago

Gerade mal 50 € kosten die Bauteile für einen #DIY-Bead-Homogenisator aus dem #3DDrucker. Und der lysiert nicht nur Zellen, etwa für die #DNA-Extraktion, sondern funktioniert auch als #Zentrifuge und Mischer. Harald Zähringer stellt ihn vor: https://www.laborjournal.de/rubric/tricks/tricks/trick252.php #LabHack

Screenshot eines Teils des im Post verlinkten Print-Artikels mit Aufmacherbild von dem darin beschriebenen Zell-Homogenisator.
G4Media 📰
5 days ago
Michael Kazarnowicz
5 days ago

"The Cosmic Serpent - DNA and the origins of knowledge" put so many ideas in my head. I need to write them down. If you're interested in biology and consciousness you want to read this book (and possibly the thoughts that follow).

It starts with insightful criticism of anthropology as a science, followed by an investigation into the knowledge of Ayahuascaeros (“shamans”).

The TL;DR: they ‘read’ DNA in certain states of mind.

1/x

#scifi #anthropology #ayahuasca #consciousness #DNA

Hamburg und Umzu
6 days ago

15-Jährige im Stadtpark vergewaltigt: Neun Männer verurteilt

Neun junge Männer sind vom Hamburger Landgericht zu Jugendstrafen verurteilt worden. Einer von ihnen muss ins Gefängnis.

https://www.ndr.de/nachrichten/hamburg/15-Jaehrige-im-Stadtpark-vergewaltigt-Neun-Maenner-verurteilt,stadtpark452.html

#hamburg #Stadtpark #Missbrauch #Vergewaltigung #Mädchen #15Jährige #Gruppe #Jugendliche #Anklage #Prozess #Sperma #DNA #Urteil #HamburgNews #Hamburg

Nonya Bidniss
6 days ago

I forgot to mention this on Black Friday so on Cyber Monday let me implore you not to purchase that great deal on sending your genome to a private corporation for "fun." The risks of doing this, many of which have not even been conceived yet by the profit machine, are not worth it for you or your current or future family. No matter what they say, you won't own your data. #DNA
p.s. I've already seen all the arguments, don't bother me with them.

Cosmin Saveanu
6 days ago

While I like SnapGene's visualization of molecular biology constructs, the proprietary ".dna" format makes me reluctant to use this software. I will forever remember how hundreds of files created in another proprietary format for DNA sequences were lost in the past when the software reading them was suddenly no longer available.

If you are using #SnapGene, it is a good practice to keep exported backups of your files in an open and readable format (EMBL, Genbank).

#molecularbiology #dna #tools

Yle Uutiset
6 days ago

Mitä paljastui DNA-kartoituksessa? Puoli seitsemän kerää lukijoiden kertomuksia

Puoli seitsemän kerää lukijoiden kertomuksia DNA-kartoituksista. Miksi olit kiinnostunut tekemään testin? Entä ilmenikö testistä jotain yllättävää, hauskaa tai jopa järkyttävää? Kerro tarinasi meille.

https://yle.fi/a/74-20061592

#DNAtestit #Perinnöllisyystiede #Tutkimus #Tiede #DNA #Joulu #Sukulaiset #Kotimaa #Terveys #Biologisetvanhemmat #Puoliseitsemän

ISOGG
1 week ago

“CRISPR–Cas9 is best known as a laboratory tool for editing DNA, but its natural function is as part of the immune system that helps certain microorganisms to fight off viruses. Now, researchers have used an algorithm to sort through millions of genomes to find new, rare types of CRISPR system that could eventually be adapted into genome-editing tools.” #isogg #dna #geneadons #CRISPR #epigenetics

Https://www.nature.com/articles/d41586-023-03697-w

EL¡AS 🇧🇷 🇵🇸
1 week ago

@gutocarvalho Eis que o #DNA roteado e as escolhas, guardadas as proporções, deviam ser abrigo contra as tempestades da vida.

A tragédia tamanho G é que não raro, ambos os grupos são os feromônios do mau ou mal e a origem de toda sorte maldades e desgraças, inclusive o famigerado Cuscuz'Klan.

Manoel tudo fotógrafava, porém depois de fotografar essas foto, "perdeu mané", a vida!

#Brasil #brazil #family #racism #religion #racismo #racisme #brooklyn #nazista #nyc #nazis

Janneke
1 week ago

"We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness." (USA 1776)

Self-evident. Hmm. And what if Allah was their Creator? (NL 2023)
#PVV #Wilders #ISLAM #DNA

Biziday 📰
1 week ago

#DNA cere ridicarea imunității fostului prim-ministru, Florin #Cîțu, precum și a foștilor miniștri ai Sănătății, Vlad #Voiculescu și Ioana #Mihăilă, pentru achiziția unui număr prea mare de vaccinuri anti-🦠#COVID, în timpul pandemiei, provocând astfel statului un prejudiciu de peste un miliard 💶#EUR. Este vorba de 52 de milioane de doze, suplimentar față de cele care ar fi fost necesare pentru întreaga populație a României.

🔗 https://biziday.ro/268444-2

#Știri #România #Sănătate

GW
1 week ago

Hijacking of the American Populist Tradition

“The Protestant ethic and the spirit of #wokeness,” Ian Buruma points out the obvious: wokeness is as old as the conversion testimony that Puritans in New England that those seeking to be considered “the elect” had to make to become “selectmen” who could vote and hold office. Indeed, the idea of “wokeness” is baked into #American historical and cultural #DNA from religious great awakenings to #political parties and campaigns.

https://www.counterpunch.org/2023/11/23/hijacking-of-the-american-populist-tradition/

demonstrators marching
TU München
1 week ago

Congratulations to Julia Herzen, Karl Duderstadt and Job Boekhoven who receive the prestigious #ERC Consolidator Grants from the ERC Research Council http://go.tum.de/320269 🥳

#xrayimaging #dna #SupramolecularChemistry

📷R.Lahn

Wie DNA-RNA-Hybride Krebs verursachen können. Forscher bestätigen die Rolle dreisträngiger Erbgut-Schleifen für die Krebsentstehung. #DNA #RNA #Krebs #Genom #Mutation #Erbgut
https://www.scinexx.de/news/medizin/wie-dna-rna-hybride-krebs-verursachen-koennen/

Ancestry Roads
1 week ago

For those of you that said no.... I thought I would share why it is useless for me to work on #pet DNA.

My pound puppy's #Ancestry is attached along with his DNA. Amazingly, his entire family looks the same.

And, his closest #DNA #relative, out of 14, is at 3%

Pictures of a Yorkshire Terrier Family tree where they all look exactly alike: brownish yorkie terrier with a red bow.
Three numbers:  0 for Close, 0 for Extended, and 14 for Distant.

This is to show results from my pound puppy's DNA relatives.
Narayoni
2 weeks ago

This study shows that in the nematode Caenorhabditis elegans, the downregulation of active TE families extends lifespan. These findings link DNA activity to aging and opens up new possibilities in medical and biological research for health improvement and age determination.
https://doi.org/10.1038/s41467-023-40957-9
#science #dna #piwipirna #epigenetics #ageing #research #naturecommunicationsjournal #openaccess
https://scitechdaily.com/aging-reimagined-how-immortal-jellyfish-dna-could-extend-human-life/

Autonomie und Solidarität
2 weeks ago

Ach.... Europas Polizeien dürfen bald mehr #Daten austauschen!

"Der Prümer Vertrag regelt, welche Daten europäische Polizeibehörden untereinander teilen dürfen․ Die EU plant seit langem, das Abkommen auszuweiten, seit Montag steht die neue Fassung․ Biometrische Daten sollen nun einfacher ausgetauscht werden können․"

https://netzpolitik.org/2023/pruemer-vertrag-europas-polizeien-duerfen-bald-mehr-daten-austauschen/

#Überwachung #datenaustausch #DNA #EPRIS #EUKommission #EUParlament #EURat #EuropäischeUnion #Fingerabdrücke #Führerscheindaten #Gesichtserkennung #Polizei

Atheism Actually
2 weeks ago

Nice one from the counter-creationism crew
-- 40 Failed Predictions? LOL NOPE, with Science Friends --
(at Creation Myths)
https://www.youtube.com/watch?v=ITx3lIVpNR4

#creationism #intelligentDesign #evolution #science #DNA #genetics #junkDNA #astronomy #geology

Ricardo Harvin
2 weeks ago

"A new watershed study has mapped over 3,000 #cell types in the #human #brain"

"This is very much like the early stages of the #HumanGenomeProject. We have now begun that journey."

Like with #DNA, no doubt the rush to "#patent" brain cell patterns is fully engaged.

https://www.sciencefocus.com/news/brain-atlas-3000-cells

OddOpinions5
2 weeks ago

I once heard Julius Marmur say

You can go from physics or math to biology, but not the other way around

[ pause ]

I know of only one physicist who has made a real contribution to biology

I think he might have mean't Seymour Benzer
https://www.pnas.org/doi/10.1073/pnas.2115546118

#DNA #Genetics #Science #Biology #AcademicChatter #Tenure

This is still one of the greatest #experiments in the #historyofscience imo. First to show #DNA is the #genetic material of #life.

INDEPENDENT FUNCTIONS OF #VIRAL #PROTEIN AND NUCLEIC ACID IN GROWTH OF #BACTERIOPHAGE https://rupress.org/jgp/article/36/1/39/30168/INDEPENDENT-FUNCTIONS-OF-VIRAL-PROTEIN-AND-NUCLEIC

Simon E. Fisher
2 weeks ago

We are looking for talented junior scientists to join our International Max Planck Research School for Language Sciences in Nijmegen, the Netherlands. Two fully-funded 4-year #PhD fellowships (2024-2028) are available to carry out cutting-edge research on #genetics and #development of human #language, with several innovative projects to choose from, co-supervised by leading researchers at the Max Planck Institute and our partners at the Radboud University. Projects include investigating rare #DNA variants in genes that cause developmental speech/language disorders, and neuroimaging #genomic analyses of language circuits in the brain.

Application portal opens Dec 4th 2023 and closes Jan 8th 2024. Full information and FAQ can be found here: https://www.mpi.nl/imprs-phd-fellowships-2024

Boosts much appreciated!

#MastodonScience #science #academia

@mpi_nl @maxplanckgesellschaft @Radboud_uni

Photograph of the outside of the Max Planck Institute in Nijmegen, surrounded by trees.
James Hawley, PhD
2 weeks ago

@alisonkiddle I'm not a working mathematician, but I use #math all the time in my day job as a computational biologist.

The short answer is that I use computers and math to study how #DNA and molecules inside #cancer cells behave and respond to treatments.

The longer answer is that I use #graphtheory, #statistics, and #biology to plan experiments, then use compression algorithms, more statistics, and computers to make accurate predictions and inferences from high throughput sequencing data.

Steven Saus [he/him]
3 weeks ago

From 11 Nov: Mummified baboons point to the direction of the fabled land of Punt - Enlarge / Drawing of a trade expedition to Punt during the reign of Queen Hatshepsut. Note... https://arstechnica.com/science/2023/11/mummified-baboons-point-to-the-direction-of-the-fabled-land-of-punt/ #ancient-dna #ancient-egypt #archeology #baboon #dna #egypt #egyptian-mummies #genetics #science

Anna Anthro
4 weeks ago

“Researchers trying to rebuild the Scottish #wildcat (Felis silvestris) population are gaining insights from ancient #genomics.

At a wildlife park in the Scottish Highlands, a captive-breeding programme is considering an audacious breeding strategy to eliminate the house-cat #DNA that has infiltrated the wildcat genome.

To help them to unpick the problem, researchers analysed the genomes of dozens of ancient and modern #cats.”

https://www.nature.com/articles/d41586-023-03451-2

Flipboard Science Desk
4 weeks ago

Researchers have long created facial approximations of people from the past. But Live Science asks: How accurate are these reconstructions? https://flip.it/FeTFZX
#Science #DNA #History

brad m
4 weeks ago

“if #cycling maintains cardiovascular performance more effectively than a $2m-a-year #antiaging regime, maybe a #bike is the only rejuvenation tool any of us really need”
“If #exercise were a drug, what’s the correct dose?”
“It’s tempting to assume that there is something like a clock encrypted in our #DNA counting down the time we have left. But that’s an unhelpful analogy” https://www.cyclingweekly.com/fitness/the-anti-ageing-face-off-dollar2m-a-year-blueprint-project-versus-the-humble-bicycle #bicycle #fitness #aging #longread

Scientific Frontline
1 month ago

Scientists at Florida State University produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 #enzyme while it cut strands of #DNA
#CRISPR #Biology #Chemistry #Science #sflorg
https://www.sflorg.com/2023/11/bio11022301.html

Das
1 month ago

Pretty big crowd at the #ISNAC2023 meeting - on #NucleicAcids #Chemistry
I thought I did ok - went over Advances in #DNA & #RNA #Polymer hybrids. Key slide ⅓ of the way through after acknowledgements & background I showed the headers, titles of the 4 papers my student has out - in Chem, Precision Chem, JACS and ACS Nano, the last one just 2 weeks ago.
Told the audience he was happy, I was happy, and I hope they would read the papers, so "you too will be happy"
Just one slight chuckle
#ProfLife

Eric Vitiello
1 month ago
Megan Smolenyak
1 month ago

Welcome home, 1st Lt. Edward Timothy McGuire. Honored to have researched your family. #hero #WWII #genealogy #DNA

https://patch.com/illinois/evergreenpark/funeral-procession-route-set-wwii-pilot-who-was-mia-80-years

Nate Gaylinn
1 month ago

I'd like to learn more about computational models of gene regulatory networks. Does anybody have pointers about that?

Boosts appreciated. :boost_requested:​

To be more specific, I'm looking for something analogous to artificial neural networks. Something very simplified and easy to implement. Something that focuses on the causal / informational / computational properties of gene regulatory networks in general.

That's probably different from models of specific gene networks, or computational biology tools for studying the genes of real organisms.

#genetics #dna #science

beSpacific
1 month ago

GSK Plc will pay #23andMe Holding Co. $20M for #GeneticTesting company’s vast #trove of #consumer #DNAData, extending a 5 yr collaboration that’s allowed the #drugmaker to mine #geneticdata as it researches new #medications. Under the new agreement, 23andMe will provide GSK with one year of access to anonymized #DNA data from the approximately 80% of gene-testing customers who have agreed to share their information for research. Really? #privacy #medicine #healthcare https://www.bloomberg.com/news/articles/2023-10-30/23andme-will-give-gsk-access-to-consumer-dna-data

skry
1 month ago

This sad empty state (You currently have no saved monsters) is for saving the creatures you make by playing a #game with #DNA.

https://askabiologist.asu.edu/monster-maker-game/

#ASU #biology dept lets you “decode a monster genome” in their possibility space of 240,240 possible monsters.

#education #science

Screenshot of a mostly empty page with a menu button on it. Text reads: 

“Monster Gallery

Your decoded monsters will appear here. You currently have no saved monsters.

Game Credits | Monster Manual | Ask a Biologist | Arizona State University
Marcel Waldvogel
1 month ago

Just ran across this platform, which seems to be really master all the #VC #Hype™:

You are a slave to a dynamic #Metaverse #AI Tamagotchi #NFT, have to train its #GeneticAlgorithm-based #DNA with immutable memories which they own (!) on the #Blockchain using #MachineLearning #ML.

They are also marketed as your perfect #DeFI trading agent (despite each having their unique designed-in random defects).

Really seems to be only targeted at investors, not at results. https://www.alteredstatemachine.xyz

Jim Wald
1 month ago

@tkinias You have *great* dinner-table conversations (AND correctly hyphenate): so glad we both appropriately migrated and reconnected here!

Lately, our dinner-table conversations have been more about #historic structures and HVAC, budget, and fundraising, but I am sure they will soon pivot to Bronze Age ancient #DNA and the role of my ancestors in inventing language and domesticating horses

Autonomie und Solidarität
1 month ago

Identität auf Vorrat - mehr als eine Million Profile - DNA Sammelwut in #Deutschland
"Polizeiliche DNA-Datenbanken wachsen in beängstigender Geschwindigkeit und werden international vernetzt. Die eingängige Begründung: Spurensammeln gegen Gewaltverbrechen wie Mord oder Vergewaltigung.
Doch das Hauptaugenmerk der biologischen #Vorratsdatenspeicherung liegt längst nicht mehr auf Kapitalverbrechen. Im Gegenteil: Es geht um eine flächendeckende präventive Erfassung, die u.a. Bagatelldelikte wie Diebstahl, Grafittisprayen oder kleine Dealereien zum Anlass nimmt.
(...)
Das Buch gibt einen umfassenden Überblick über den aktuellen Stand der DNA-Datenspeicherung. Die Autor_innen untersuchen die gefährliche Weiterentwicklung der DNA-Analyse. Sie entmystifizieren die »Wahrheitsmaschine« #DNA und zeigen Grenzen und Fehlerquellen im kriminaltechnischen Alltag auf. Sie dokumentieren ermutigende Beispiele für Protest- und Widerstandsaktionen. Und nicht zuletzt bietet das Buch praktische und juristische Tipps, wie man sich gegen das Wattestäbchen im Mund und die Speicherung von DNA-Profilen wehren kann."

Das Buch erschien bereits 2017 in zweiter Auflage...
https://shop.gen-ethisches-netzwerk.de/buch/45-identitaet-auf-vorrat.html

#Buch als #PDF:
https://shop.gen-ethisches-netzwerk.de/index.php?controller=attachment&id_attachment=28

#Polizei #Repression #Staat #Privacy #Data

In blau steht der Titel auf weißem Hintergrund 

Gen-ethisches Netzwerk (Hg.)
"Identität auf Vorrat"
Zur Kritik der DNA-Sammelwut

darunter zu sehen ist ein blaues geknicktes Wattestäbchen. in orangenem kasten steht darunter in weiß: "2. Auflage gratis als PDF"

darunter in grün ganz klein geschrieben der Verlag "Assoziation A"
Autonomie und Solidarität
1 month ago

Der polizeiliche Zugriff auf DNA-Daten - Strategien der Gegenwehr #Zine
"Was tun, wenn die #Polizei eine Speichelprobe verlangt, um Deine #DNA zu analysieren?
Was, wenn Dein DNA-Profil schon in der DNA-Datenbank des BKA gespeichert ist?
Und was, wenn die #Ermittlungsbehörden Dich wegen eines Massengentests, einer so genannten DNA-Reihenuntersuchung, anschreiben?
Seit einer Strafrechtsreform von 2005 wurde der polizeiliche Zugriff auf die DNA-Daten enorm ausgeweitet – und der Rechtsschutz empfindlich ausgehöhlt. Gleichzeitig gilt: Je diffuser die Rechtslage, desto mehr Spielräume gibt es, sich – auch mit rechtlichen Mitteln – zur Wehr zu setzen. Und je mehr die biologische Vorratsdatenspeicherung zunimmt, desto mehr ist Widerstand angesagt."
August 2023 / Gen-ethisches Netzwerk e.V.
PDF Download:
https://shop.gen-ethisches-netzwerk.de/index.php?controller=attachment&id_attachment=57
Webseite:
https://shop.gen-ethisches-netzwerk.de/broschuere/105-der-polizeiliche-zugriff-auf-dna.html

#Überwachung #Kontrolle #Repression #Staat #Herrschaft #Antireport #Privacy #Data

Zine Cover 

Grüner Hintergrund

Darauf steht in weiß in einem kleinen blauen kasten 

"der Polizeiliche Zugriff auf DNA-Daten"
Darunter in blau in weißem kasten
"Strategien der Gegenwehr"

Darunter ein Bild der Polizei und ein bild eines genoms vor einer behörde, zu dem bild für ein blauer strich zu einem weißen kasten auf welchem "Gene und Genome" stehen

darunter zu sehen weitere Genome

ganz unten steht in blau. GeN: gemeinnützig, kritisch, interdisziplinär
David
1 month ago

I stumbled upon a #podcast series on #DNA testing and #genealogy.

BBC Radio 4 -The Gift

Across six episodes, Jenny Kleeman meets the men and women whose lives changed forever after they opened a box that contained a DNA test. Exposing scandals, upending identities, solving mysteries and delivering life-changing news - Jenny investigates what happens when genealogy, technology and identity collide.

https://www.bbc.co.uk/programmes/p0gd2dgb

A graphic for the podcast series. An image of someone (hand only) unboxing a DNA testing kit.  The show title "The Gift" at the top
DPiercy
1 month ago

Found this, Thomas More is an ancestor of mine, this is most definitely going in my family history library! #familyhistory #books #ancestry #DNA

The life of Thomas More
Tisha Tiger
1 month ago

Please consider modifying your #DNA, I suppose?

"Hacker leaks millions more 23andMe user records on cybercrime forum" : https://techcrunch.com/2023/10/18/hacker-leaks-millions-more-23andme-user-records-on-cybercrime-forum/

Doc Impossible
1 month ago

You've probably heard from transphobes about how "you can't change your DNA," so nothing you do in transition really matters. "Basic biology," they whinge. Well... what about intermediate biology?

This week on #StainedGlassWoman, come and see How HRT Rewrites Your DNA by just plain turning off the parts you don't need and turning on the ones you do! Now with more wedding photos, from *another* queer wedding.

#FtM #MtF #Nonbinary #trans #transjoy #Biology #HRT #DNA

https://stainedglasswoman.substack.com/p/how-hrt-rewrites-your-dna

Megan Smolenyak
1 month ago

Interesting, but I already know I'm a spice-loving, risk-taking, eat/drink-anything, boogie-down, non-sneezing introvert - and with the exception of the hothead trait (self-induced 🌶), I know exactly which came from Mom, from Dad, and from both!
#genealogy #DNA
https://www.prnewswire.com/news-releases/ancestry-launches-parental-traits-inheritance-bringing-a-deeper-understanding-of-which-parents-dna-has-the-most-influence-on-their-offsprings-unique-dna-makeup-301959040.html

vollkorntomate
1 month ago

Apparently (according to 23andme) the data was obtained through credential stuffing (i.e. trying out username/password combinations that have been leaked elsewhere before), and not due to a security issue on 23andme’s side.

While one could easily blame the victims for reusing their passwords and not enabling 2FA, I think businesses dealing with such sensitive data like 23andme should have an even stronger focus on their users’ data security. Requiring long passwords, checking against previously leaked passwords and making 2FA mandatory (and not just optional) are three easy steps that (together) would have probably prevented this data breach.

https://www.bleepingcomputer.com/news/security/hacker-leaks-millions-of-new-23andme-genetic-data-profiles/

#23andme #databreach #dna

Alan Kotok
2 months ago

A new company is underway that says it adapts the gene editing technique Crispr to make detecting nucleic acid targets like DNA or RNA faster and simpler.

https://sciencebusiness.technewslit.com/?p=45347

#News #Press #Science #Business #StartUp #Biotechnology #Chemistry #Engineering #GeneEditing #Crispr #DNA #RNA #Proteins #PCR #University #Finance #VentureCapital

Flipboard Science Desk
2 months ago

What happens when you add spider DNA to silkworms? Big Think explains.
https://flip.it/J49f.L
#Science #Biology #Spiders #DNA #Silkworms

Falk Steiner
2 months ago

EU-Kommissar @thierrybreton.bsky.social hat einen neuen Gesetzesvorschlag angekündigt: den #DigitalNetworksAct (#DNA)
Ein Ziel: weniger, größere Telekommunikationsunternehmen. Auch das Thema der trusted vendors will Breton massiv ausweiten.... Meine Analyse, die gestern bei heise online erschien.
https://www.heise.de/meinung/Digital-Networks-Act-Bretons-spaeter-Plan-fuer-die-Telekommunikationsbranche-9331873.html?utm_term=Autofeed&utm_medium=Social&utm_source=LinkedIn&trk=feed-detail_main-feed-card_feed-article-content

📨 Latest issue of my curated #cybersecurity and #infosec list of resources for week #40/2023 is out! It includes the following and much more:

🇺🇸 🗳️ D.C. Board of #Elections confirms voter data stolen in site hack
🔓 🪪 #MGM Resorts confirms hackers stole customers’ personal data during #cyberattack
🔓 🧬 #DNA testing service 23andMe investigating theft of user data
🔓 🎧 #Sony confirms #databreach impacting thousands in the U.S.
📱 💥 Lyca Mobile Group Services Significantly Disrupted by Cyberattack
🔓 🕵🏻‍♂️ #NATO investigating breach, #leak of internal documents
🔓 🇪🇺 European Telecommunications Standards Institute Discloses Data Breach
🔓 🏨 #MotelOne discloses data breach following #ransomware attack
🇰🇵 💰 North Korea's #Lazarus Group Launders $900 Million in #Cryptocurrency
🇧🇪 🇨🇳 #Alibaba accused of ‘possible espionage’ at European hub
🇨🇳 #China-linked cyberspies #backdoor #semiconductor firms with #CobaltStrike
🥸 Meet LostTrust #ransomware — A likely rebrand of the #MetaEncryptor gang
🇬🇾 🇨🇳 #Guyana Governmental Entity Hit by #DinodasRAT in #CyberEspionage Attack
🇷🇺 🇺🇸 #FBI most-wanted Russian hacker reveals why he burned his passport
🇺🇸 🏥 #FDA cyber mandates for #medicaldevices goes into effect
☁️ 🔓 Number of Internet-Exposed #ICS Drops Below 100,000
☁️ #Microsoft Warns of Cyber Attacks Attempting to Breach Cloud via #SQL Server Instance
🦠 📈 #QakBot Threat Actors Still in Action, Using Ransom Knight and Remcos RAT in Latest Attacks
🔓 🍏 #Apple Warns of Newly Exploited iOS 17 Kernel Zero-Day
🎣 🧑🏻‍💼 US Executives Targeted in #Phishing Attacks Exploiting Flaw in Indeed Job Platform
🦠 🏦 #Zanubis #Android Banking Trojan Poses as Peruvian Government App to Target Users
🦠 🇮🇷 Iranian APT Group #OilRig Using New Menorah #Malware for Covert Operations
🔐 ☁️ #Amazon to make #MFA mandatory for 'root' #AWS accounts by mid-2024
🛡️ 🧅 #Microsoft Defender no longer flags #Tor Browser as malware
👀 X-Force uncovers global #NetScaler Gateway credential harvesting campaign
🐛 💰 Zero-days for hacking #WhatsApp are now worth millions of dollars
🩹 #Cisco fixes hard-coded root credentials in Emergency Responder
🔓 Vulnerabilities in #Supermicro BMCs could allow for unkillable server #rootkits
🔓 🐧 Looney Tunables: New #Linux Flaw Enables Privilege Escalation on Major Distributions
🐍 Warning: #PyTorch Models Vulnerable to Remote Code Execution via ShellTorch
🩹 Microsoft Edge, Teams get fixes for zero-days in #opensource libraries
🔓 🔥 Live Exploitation Underscores Urgency to Patch Critical WS-FTP Server Flaw
☁️ Cloudflare #DDoS protections ironically bypassed using #Cloudflare

📚 This week's recommended reading is: "8 Steps to Better Security: A Simple Cyber Resilience Guide for Business" by Kim Crawley

Subscribe to the #infosecMASHUP newsletter to have it piping hot in your inbox every week-end ⬇️

https://infosec-mashup.santolaria.net/p/infosec-mashup-week-402023

Nando161
2 months ago

Jesus fucking Christ. Do not trust any of these fucking #ancestry #companies with your #data. #dna

ProPublica
2 months ago

Decades-Old Trove of #DNA Evidence, Collected by a #Maryland Doctor, Leads to a Serial #Rape Arrest

A ProPublica investigation highlighted a critical collection of evidence and inspired a law to preserve it.

Now, that evidence has been used to charge a man with three rapes.

https://www.propublica.org/article/decades-old-trove-of-dna-evidence-leads-to-serial-rape-arrest-maryland?utm_medium=social&utm_source=mastodon&utm_campaign=mastodon-post

Ele Willoughby, PhD
2 months ago

While Rosalind Franklin (1920 – 1958), #chemist & #crystallographer is now remembered because her x-ray diffraction images which were instrumental to discovering double-helix structure of #DNA, I am posting her for #SciArtSeptember theme charcoal, because of her important contributions to #carbon research.

⁠She made invaluable contributions across physics, chemistry & biology, working to determining the structure of #RNA,

🧵1/2
#linocut #printmaking #WomenInSTEM #histstm #sciart#MastoArt

My linocut portrait of Rosalind Franklin (1920 – 1958), in a gradient of magenta from her shoulders up through dark blue to her hair. Her necklace is a double helix of DNA. Her brooch is the Tobacco Mosaic Virus. The pattern on her jacket is based on her publication of the structure of non-graphitizing carbon.
⁠
Behind her in shades of robin’s egg blue is an image of the famous X-ray crystallographic Photo 51, produced by her grad student Gosling and important to deducing the structure of DNA.
Keith D Johnson
3 months ago

2. "The sheer quantity of chemicals being dumped into the environment is quickly growing. UNEP counted the annual release of toxic chemicals in 2006 at 6 million tons, but Worldometer estimates the current release at 10 million tons—a 67% increase in a little over a decade.
Perhaps the most frightening biological impact of many endocrine-disrupting chemicals is their tendency to alter #DNA expression in ways that can be inherited by subsequent generations. It’s long been known that #environmental factors (#food, #air, #water) can cause genes to be switched off or on, or dial their expression up or down. Sometimes the effects are transgenerational, and continued presence of chemicals in the environment can amplify biological impacts from one generation to the next."

Jew Of the Day
3 months ago

✡️ Today's Jew of the Day is Rosalind Franklin!

Rosalind Elsie Franklin was a chemist and X-ray crystallographer whose pioneering work paved the way for many huge scientific advances, specifically around DNA, of which she is considered by many to be an unsung hero, outlining the composition and basic structure of the DNA structure before Watson and Crick.

Franklin's early work was on using X-ray and displacement to determine the porousness of coal, which was of critical importance during WW2, as it determine coal's applicability as both a fuel source and as a possible filter in gas masks, etc.

After the war, she went on to work on biology, where she studied the structure of RNA viruses.
Her she made multiple discoveries, including that of protein molecules arranged in a helix. She even presented her findings at a lecture where Watson attended, but he did not recognize her findings.

#JewOfTheDay #scientist #biologist #DNA #BritishJews #Jewdiverse

Mark Pesce
3 months ago

Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates

"Taken together, these results demonstrate safety, biodistribution, and in vivo proviral #DNA editing following IV administration of EBT-001, supporting the further development of CRISPR-based gene editing as a potential therapeutic approach for #HIV in humans..."

Another miracle.

https://www.nature.com/articles/s41434-023-00410-4

Kent Brewster
3 months ago

Now more than ever I'm glad I didn't mess around with 23andMe. #privacy #dna https://theintercept.com/2023/08/18/gedmatch-dna-police-forensic-genetic-genealogy/

Nonya Bidniss
3 months ago

I have been telling people for about 14 years to never, ever provide your DNA to a commercial firm. If you need a medical DNA test, do it only through your doc with a certified medical lab.

Police Are Getting DNA Data From People Who Think They Opted Out - Forensic genetic genealogists skirted GEDmatch privacy rules by searching users who explicitly opted out of sharing DNA with law enforcement. #privacy #DNA
https://archive.is/LUC20

Flipboard Science Desk
4 months ago

"Oetzi the Iceman has a new look. Decades after the famous glacier mummy was discovered in the Italian Alps, scientists have dug back into his DNA to paint a better picture of the ancient hunter."

The AP reports: https://flip.it/y5MDXD

#Anthropology #Italy #Turkey #Science #DNA

Lorry
4 months ago

When #Trump is booked at the Fulton Country Jail in #Georgia - He will be mugshotted and fingerprinted - But can they take #DNA from him?

#Law #Legal #Police #Question
#IReallyWantToTypeGaolThere

Moritz Negwer
4 months ago

Preprint alert! Our lab developed targetable #DNA origami #nanoparticles, which we then image throughout the entire (transparent) mouse body using #lightsheet #microscopy.

Our DNA origami were able to target immune cells, as well as a subset of cancer metastases in the lung.

Preprint:
https://www.biorxiv.org/content/10.1101/2023.07.24.550304v1.full.pdf

Explainer thread:
https://bird.makeup/users/erturklab/statuses/1686331791022448640

#preprint #tissueclearing

Graphical Abstract. Top-left panel: DNA origami production, showing assembly of DNA-rod bundles in bacteria, fluorophore targeting, and an electron microscope picture of the result. 

Lower-left panel: In vivo application by intravenous injection in mice. 

Lower-central panel: In vivo quality control, showing low immunogenicity and in-vivo 2-photon imaging, showing clearance from the blood stream. 

Left panel: Whole-body biodistribution: 3D view of a transparent mouse, with cutouts detailing the organs that the DNA origami has been found in.
Lorry
4 months ago

Dammit, I read an #article last week that I think I found here, about a species of bird, I think, that inherited newly learned predator evasion techniques in the next generation by a change in #DNA

Does anyone know what it was? I don't think I was dreaming!

#Genetics #Genome #NaturalSelection #Nature vs #Nurture vs #GeneEditing

AfterDawn
4 months ago

DNA toi Suomeen myyntiin Googlen Pixel-puhelimet

Myyntiin saapuivat Pixel 7, Pixel 7a, Pixel 7 Pro ja Pixel 6a -mallit eli Pixel Foldia ei valikoimasta löydy. Jo aiemmin Pixeleitä ovat myyneet mm. Verkkokauppa ja Gigantti.

Google ei virallisesti myy Pixel-mallistoa Suomessa.

https://www.puhelinvertailu.com/uutiset/2023/07/28/dna-pixel-7-7-pro-7a-6a-puhelimet-hinta

#DNA #GooglePixel #puhelimet #uutiset

AkaSci 🛰️
4 months ago
AkaSci 🛰️
4 months ago

Interesting article on "Rosalind Franklin’s true role in the discovery of DNA’s double helix."

"Rosalind Franklin’s role in the discovery of the structure of DNA may have been different than previously believed. Franklin wasn’t the victim of data theft at the hands of James Watson and Francis Crick, say biographers of the famous duo. Instead, she collaborated and shared data with Watson, Crick and Maurice Wilkins."

https://www.sciencenews.org/article/rosalind-franklin-dna-structure-watson-crick
#RosalindFranklin #DNA
3/n

AkaSci 🛰️
4 months ago

Below is the famous Photo 51, an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber taken by Raymond Gosling, a grad student working under Rosalind Franklin in May 1952 at King's College London.

Watson and Crick used characteristics and features of Photo 51, together with evidence from multiple other sources, to develop the chemical model of the DNA molecule.

Cartoon explanation by Dr. Emily Willoughby.
https://en.wikipedia.org/wiki/Photo_51
#RosalindFranklin #DNA
2/n

AkaSci 🛰️
4 months ago

Happy Birthday Rosalind Franklin (25 July 1920 – 16 April 1958), British chemist and X-ray crystallographer, whose contributions led to the discovery of the double helix structure of DNA, although they were largely unrecognized during her life. The Nobel Prize in Physiology or Medicine in 1962 went to Crick, Watson, and Wilkins. Watson suggested that Franklin would have ideally been awarded a Nobel Prize in Chemistry, along with Wilkins, but for her untimely death.
#RosalindFranklin #DNA
1/n

Artistic illustration of Rosalind Franklin from https://www.esa.int/ESA_Multimedia/Images/2020/07/Artistic_illustration_of_Rosalind_Franklin