#Pirola
Here's the latest variant picture for New South Wales, Australia.
As of late November, EG.5.* "Eris" (59%) was still dominant.
BA.2.86.* "Pirola" (11%) began rising steadily from late October onwards.
#COVID19 #Australia #NSW #Sydney #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
🧵

▫️Die #COVID-19 Welle steigt und steigt weiter.
▫️Bei den Varienten beginnt nun auch in Österreich der #Pirola-Abkömmling #JN1 die anderen zu überholen. JN.1 ist noch immunevasiver als Pirola, sie entkommt den früheren Impfungen sehr gut.
▫️Die upgedatete XBB-Impfung bietet auch gegen JN.1 einen guten Schutz.
▫️Harmlos ist die Welle nicht, wie man an den vielen stationären Aufnahmen sieht. Von #LongCovid ganz zu schweigen.




Antoine FLAHAULT (@FLAHAULT): "Le remplacement des lignées XBB par celles du sous-variant BA.2.86 d’Omicron et de ses descendants (en tête JN.1) en l’espace de trois mois est impressionnant en Europe. Ici les données de séquençage pour la Belgique. #Pirola #COVID19" | nitter
https://nitter.d420.de/FLAHAULT/status/1732025686301282431#m
JN.1 (fast Pirola) fractions as per LolliPop (https://github.com/cbg-ethz/cowwid). The table shows the most current values (Nov 18-20) and values since 4 weeks before.
Highest: 46% (SZ), 44% (GE). Largest fraction in 5 of 14 plants.


Here's the latest variant picture for the Netherlands.
As of late November, EG.5.* "Eris" (32%) was still dominant, but fading quite rapidly.
BA.2.86.* "Pirola" (28%) began rising strongly during November.
There's also a significant late resurgence of XBB.1.5.* "Kraken" (20%).







Here's the latest variant picture for "Australia".
As of mid-November, EG.5.* "Eris" (60%) was still dominant.
BA.2.86.* "Pirola" (13%) began rising during November.
#COVID19 #Australia #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
🧵

Here's the latest variant picture for the sub-lineages of BA.2.86.* "Pirola", at the "Global" level.
JN.1 has taken over as the dominant sub-lineage, benefitting from it's Spike:L455S mutation
The second chart uses a log scale, which helps clearly compare exponential growth rates.


Wichtiges Preprint:
Der aktuelle XBB #Impfstoff wirkt gut gegen die neuen #SARSCoV2 Varianten:
Bei Probanden mit der kompletten Vorimmunisierung (Grundimmunisierung 2021 + Booster im Frühling 2022 + bivalenter Herbstbooster 2022) führt der aktuelle XBB Booster zu einer guten Antikörperantwort, auch gegen die neuen Varianten wie zB JN.1, ein Abkömmling von BA.2.86 #Pirola mit noch größerer Immunflucht. Das ist bei Probanden ohne vorherige Infektion, nach #COVID19 durch das ursprüngliche #Omikron und nach einer Infektion durch XBB.
Ein gewisses Immunimprinting (geringere Immunantwort auf neue Varianten) ist zwar auch hier zu sehen, aber es war nicht sehr stark ausgeprägt.




Here's the latest variant picture for Tasmania, Australia.
As of mid-November, EG.5.* "Eris" (68%) was still dominant.
BA.2.86.* "Pirola" (17%) began rising during October.
#COVID19 #Australia #Tasmania #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
🧵

Here's the latest variant picture for South Australia.
As of mid-November, EG.5.* "Eris" (50%) was still dominant.
BA.2.86.* "Pirola" (20%) began rising during October.
#COVID19 #Australia #SA #Adelaide #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
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🇺🇸 US: COVID variant BA.2.86 triples in new CDC estimates, now 8.8% of cases
Nearly 1 in 10 new COVID-19 cases in the U.S. are from the BA.2.86 variant, the Centers for Disease Control and Prevention estimated Monday, nearly triple what the agency estimated the highly mutated variant's prevalence was two weeks ago.
#COVID19US #BA286 #Pirola @auscovid19
Source: https://www.cbsnews.com/news/covid-variant-ba-2-86-triples-in-new-cdc-estimates/
JN.1 (fast Pirola) fractions as per LolliPop (https://github.com/cbg-ethz/cowwid). The table shows the most current values (Nov 11-13) and values since 4 weeks before.
Highest: 31%, for GE.
EG.5* is at >40% at 7 of 14 plants.

The World Health Organisation (WHO): BA.2.86 upgraded to Variant of Interest (VOI) : 21 November 2023
@WHO #BA286 #Pirola #COVIDisNotOver @auscovid19
Source: https://www.who.int/activities/tracking-SARS-CoV-2-variants
Tracking BA.2.86 "Pirola" variant in Australia
🔸Total sequences: 8⃣5⃣
(39 sequences in the past 4 weeks)
🔹SA: 2⃣7⃣sequences
🔹NSW: 2⃣1⃣sequences
🔹QLD: 1⃣9⃣sequences
🔹TAS: 1⃣0⃣ sequences
🔹WA: 6⃣sequences
🔹VIC: 2⃣sequences

JN.1 (fast Pirola) fractions as per LolliPop (https://github.com/cbg-ethz/cowwid). The table shows the most current values (Nov 4-6) and values since 4 weeks before.
Highest: 22%, for LU and SZ.
EG.5* is at >40% at 9 of 14 plants.
#JN.1 ist eine Sublinie von #Pirola (BA.2.86) und wurde im September entdeckt. Mittlerweile wurde die #Variante in mehr als zwölf Ländern nachgewiesen. Nun auch in #Deutschland. Im aktuellen Wochenbericht des #Robert-Koch-Instituts taucht JN.1 erstmals auf. Demnach macht die neue Variante derzeit zwei Prozent des Infektionsgeschehens in Deutschland aus. #Eris (EG.5) dominiert mit 53 Prozent jedoch weiterhin. #Pirola (BA.2.86) macht mittlerweile zehn Prozent aus. Die stark mutierte Variante kann schneller in die Zellen eindringen und ist deutlich ansteckender. Experten befürchten, dass der #Pirola-Nachfolger #JN.1 dies möglicherweise noch toppen könnte. Im Gegensatz zu Pirola habe JN.1 eine weitere #Mutation am #Spike-Protein. dadurch sei die Variante "noch immun-evasiver", sagt Infektiologen Thomas Russo von Buffalo #Universität in New York gegenüber "Prevention". JN.1 sei "hinterlistig". Es bestehe die Gefahr, dass nun deutlich mehr Infektionen geben könnte. [...] Zu den häufigsten #Symptomen zählen Kopfschmerzen, Abgeschlagenheit, #Gliederschmerzen, laufende oder verstopfte Nase, Halsschmerzen, Niesen, Husten, eventuell #Störungen des Geruchs- und Geschmackssinns. Die #Pirola-Variante weist jedoch ungewöhnliche Symptome wie #Hautausschlag, #Schwellungen im Mund, #Geschwüre auf der Zunge, rote und wunde #Finger oder #Zehen, #Durchfall, heisere Stimme sowie juckende oder rote #Augen auf.<<#Corona-Mutation JN.1 breitet sich in Deutschland aus! Wissenschaftler befürchten mehr Infektionen
https://www.msn.com/de-de/gesundheit/medizinisch/coronavirus-wissenschaftler-in-panik-neue-corona-mutation-breitet-sich-in-deutschland-aus/ar-AA1k59wk?ocid=winp2fptaskbar&cvid=0c55cbe4ac2c44098fb6d8a96a0e0751&ei=35
Darum: #Maske tragen!
Tracking BA.2.86 "Pirola" variant in Australia
🔸Total sequences: 7⃣5⃣
(32 sequences in the past 4 weeks)
🔹SA: 2⃣7⃣sequences
🔹NSW: 2⃣1⃣sequences
🔹QLD: 1⃣9⃣sequences
🔹WA: 6⃣sequences
🔹VIC: 2⃣sequence

JN.1 (fast Pirola) fractions as per LolliPop (https://github.com/cbg-ethz/cowwid). The table shows the most current values (Oct 28-30) and values since 4 weeks before.
Highest: 18%, for Laupen (BE). EG.5* is at >40% at 11 of 14 plants.

Assuming that relative growth would not slow down, we might be reaching dominance for JN.1 in Geneva at the present time.
Looking at bed occupancy, as of today Nov 13, we do not see a signal for higher use of intermediate or intensive care.


Covid-19: variante JN.1 está em mais de 10 países
#VarianteÔmicron #VarianteDoCoronavírus #Vacinação #Pirola #Covid #MedicinaESaúde
JN.1 (fast Pirola) fractions as per LolliPop (https://github.com/cbg-ethz/cowwid). The table shows the most current values (Oct 21-23) and values since 4 weeks before.
Highest: 13%, for Schwyz. EG.5* is at >40% at 13 of 14 plants.

Tracking BA.2.86 "Pirola" variant in Australia
🔸Total sequences: 4⃣4⃣
(29 sequences in the past 4 weeks)
🔹NSW: 2⃣1⃣sequences
🔹SA: 1⃣1⃣sequences
🔹QLD: 6⃣sequences
🔹WA: 5⃣sequences
🔹VIC: 1⃣sequence
Here's an animated map showing the spread of the new JN.1 sub-lineage of the BA.2.86 "Pirola" variant.
Starting from the presumed origin in Luxembourg in late August, over 300 samples have been reported so far from 28 countries.
Locations are approximate - typically country and state/province.
Here's the latest variant picture for Queensland, Australia.
As of mid-October, EG.5.* "Eris" (60%) was still dominant.
BA.2.86.* "Pirola" (4%) began rising during October.
#COVID19 #Australia #QLD #Brisbane #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
🧵
Here's the latest variant picture for New South Wales, Australia.
As of late October, EG.5.* "Eris" (57%) was still dominant.
BA.2.86.* "Pirola" (6%) began rising in late October.
#COVID19 #Australia #NSW #Sydney #EG_5 #Eris #BA_2_86 #Pirola @auscovid19
🧵
(Mirroring old account)
Here's an alteration I made of a FANTASTIC flowchart by "Your Local Epidemiologist" on Substack:
https://yourlocalepidemiologist.substack.com/p/state-of-affairs-oct-12
I amended it with TRG's COVID clan nicknames and added an arm (or whatever it's called) for BA.5.
#Covid #Covid19 #CovidIsNotOver #BA5 #BA286 #CovidClans #Variants #Arcturus #Eris #Pirola
The 11 COVID symptoms you need to know as Pirola (BA.2.86) strain sweeps through UK.
🔹Continuous cough
🔹High temperature, fever or chills
🔹Loss of, or change in, your normal sense of taste or smell
🔹Shortness of breath
🔹Unexplained tiredness, lack of energy
🔹Muscle aches or pains that are not due to exercise
🔹Not wanting to eat or not feeling hungry
🔹Headache that's unusual or longer lasting than usual
🔹Sore throat, stuffy or runny nose
🔹Diarrhoea
🔹Feeling sick or being sick
#COVID19 #Pirola #BA286 @auscovid19
Source: https://www.mirror.co.uk/news/health/11-covid-symptoms-you-need-31111136
Here's the latest variant picture for the United States.
The EG.5.* "Eris" variant (41%) has been dominant, and is still growing.
An early read on the recent growth of BA.2.86.1 "Pirola" gives it a growth advantage of 15% per day over EG.5.*, which predicts a crossover in a couple of weeks.
The sample volumes seem representative up to September 22.
#COVID19 #US #EG_5 #Eris #BA_2_86 #Pirola
Interactive genomic sequencing dataviz, code, acknowledgements and more info here:
https://github.com/Mike-Honey/covid-19-genomes#readme
Orrr.... 🙄
"In summary, we found that BA.2.86 is antigenically distinct from XBB.1.5 and previous #Omicron variants, and can evade XBB-induced and XBB-effective neutralising antibodies targeting various epitopes. "
#pirola #BA286 #XBB15 #Covid19 #CovidIsNotOver #BringBackMasks
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00573-X/fulltext
Heads-up: Sato Lab just published their findings on #covid variant BA.2.86 (#Pirola) and call it "one of the most highly immune evasive variants ever"
Link: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00575-3/fulltext
So, wore a mask to the supermarket for the first time in a while and... it was fine.
I know lots of folk have never stopped masking, but re-masking is also doable. Just putting it out there in case anyone feels resistance or stuckness.
There's nothing strange about not wanting to be ill, nothing strange about wanting to protect others.
https://www.theguardian.com/world/2023/sep/16/nhs-uk-prepared-covid-winter-pirola-variant
Q. is the #Pirola variant of #Coronavirus likely to offer the #Tories another chance to mishandle a #pandemic?
The Pirola variant is spreading, covid monitoring & data gathering has been stripped back, #vaccination *is* getting under way but is limited by capacity & demographic(s)... no social measures (#masking, #socialdistancing) are as yet being publicised.
Could this be about to be a very difficult #winter? The trouble is as yet we have no good way of knowing until well down that road!
New roundup: https://www.patreon.com/posts/pandemic-roundup-89254762
- CDC: 54% of hospitalized kids have no underlying health problems
- UK: 2.6M out of work from long-term sickness
- Novavax: FDA approval in “days not weeks”
- Long C19 sufferers self-experimenting w/nicotine patches
- CDC meeting slides reveal high US prevalence of long C19
- Actor Will Keenan attacked, blinded for masking
#Covid #CovidIsntOver #MaskUp #Novavax #Moderna #Pfizer #LongCovid #Diabetes #CovidInquiry #HanSoHee #Eris #Pirola #variants #PHAC #CDC
#IDMastodon #COVIDisnotover #pirola on the move .#MaskUp 😷to protect the immunosuppressive patients .Cancer patients are at increased risk for severe complications from #COVID19 due to factors like aging, immunosuppression, & having other diseases or medical conditions at the same time.
New:
-FDA: updated vax “not intended for everyone”
-Whoopi Goldberg on 3rd infection
-CDC: long covid in 38+ million US adults
-CVS ends Medicaid Paxlovid
-Biden mocks masking, US ER visits at winter levels
-Large, bad Biobot correction
-How to support friends w/long covid
-Resources galore!
Link, never paywalled: https://www.patreon.com/posts/pandemic-roundup-88906343
#MaskUp #Covid #LongCovid #Biden #Paxlovid #Booster #Novavax #WhoopiGoldberg #CovidIsntOver #CDC #Pirola #LongCovidKids #Metallica #JamesHetfield #USOpen
🇰🇷 Korea reports 1st case of Pirola (BA.2.86), the new variant of Covid-19.
The Korean health authorities reported the first confirmed case of a Korean patient infected with the BA.2.86 variant on Aug. 31
#COVID19 #Korea #BA286 #Pirola @auscovid19
Source: https://www.koreabiomed.com/news/articleView.html?idxno=22007
New:
–Covid is causing severe allergies to hair dye
–Study: the less time you’re exposed, the lower your chances of infection
–US rise continues; Hawai’i leads in hospitalizations
–CDC compares (still evolving) BA.2.86/Pirola to Omicron
–Indoor Air Quality now regulated in Ireland
–Masks back after outbreak at Warner Bros./Discovery
More: https://www.patreon.com/posts/pandemic-roundup-88525377
#CovidIsntOver #MaskUp #Covid #LongCovid #Hawaii #Discovery #Ireland #IAQ #Omicron #Pirola #KeepMasksInHealthcare #MasksInHealthcare
#IDMastodon #CovidIsNotOver #MaskUp 😷 #PublicHealth Based on currently available data, updated #COVID19 vaccines targeting the XBB.1.5 variant are expected to be effective against BA.2.86 “#pirola” a highly mutated new #SARSCoV2 variant—for reducing severe disease & hospitalization
Vaikka uskallankin veikata Suomeen korona-aaltoa syksylle, niin rohkeus ei riitä sen korkeuden ja käyrän alle jäävän pinta-alan ennustamiseen. Jos on pakko arvata, niin sanoisin ainakin ensimmäisen aallonhuipun jäävän vuosien 2022–2023 matalimmaksi, mutta en yllättyisi vaikka näkisimmekin enemmän koronaa kuin koskaan aiemmin.
Rauhallisempaa epidemiaa lupailee minusta se, että muualla, ainakin Yhdysvalloissa ja Alankomaissa, kesä-heinäkuussa alkanut aalto osoittaa jo merkkejä kasvun hidastumisesta. Uudet variantit (ja ihmisten käyttäytymisen muutokset yhä jossain määrin) aiheuttavat kuitenkin jatkuvaa epävarmuutta. Taitaa vierähtää tovi ennen kuin nähdään, seuraako esim. #Pirola-variantista talven aikana mitään ihmeellistä maailmalla, saati sitten Suomessa.
Ainakaan mitään sellaista ei ole odotettavissa, että näkisin syytä lakata suojautumasta koronalta. Flunssaakaan ei ole tullut yhtään ikävä.
Kuvien lähteet:
Yhdysvallat: https://biobot.io/data/covid-19
Alankomaat: https://www.corona-lokaal.nl/locatie/Nederland/waterzuivering/Nederland
Here's an update on the reported samples of the new BA.2.86 "Pirola" variant, vs the overall sample counts.
I've created a page for this in my dataviz, based on the table format Cornelius Roemer posted earlier.
https://twitter.com/CorneliusRoemer/status/1694695153020084496?s=20
With the interactive filters, you can choose any Lineage, date range and/or mix of Continents and Countries to suit.
Interactive genomic sequencing dataviz, code, acknowledgements and more info here:
https://github.com/Mike-Honey/covid-19-genomes#gisaidorg-with-nextclade-lineages---weekly-table