More than 100 'magic mushroom' genomes point the way to new cultivars - Cell Press https://phys.org/news/2023-12-magic-mushroom-genomes-cultivars.html #psilocybin #MagicMushrooms #hallucinogens #psychedelics
I'm copying a public post below from an interesting Assistant Professor of Philosophy and Data Science at UNCC (not a medical doctor or psychologist).
Everything he is discussing is TENTATIVE but very interesting. I'm sending this out now because there is so little in the popular press about what can actually be done to help people with brain fog and other Long COVID symptoms. The research is still very early, and of course medical professionals should be consulted.
1) The article link from Nature Magazine describes brain damage caused by SARS-CoV-2 related to cell death and especially to synapse loss, leading to cognitive impairment.
2) The study in Bioelectric Medicine is extremely small, yet shows the potential of nicotine patches in the treatment of Long COVID symptoms including brain fog. (Another paper from the same publication also goes into why nicotine might help with Long COVID: https://bioelecmed.biomedcentral.com/articles/10.1186/s42234-023-00104-7 )
3) He then points to a study on the NIH PubMed site reporting the encouragement of synapse growth from psilocybin.
4) A comment in the discussion thread also links to a British Medical Journal article on Metformin improving Long COVID symptoms ( https://www.bmj.com/content/381/bmj.p1306 )
There's further speculation in the discussion thread that other psychoactive substances might be helpful. There are perhaps AI bots in the discussion thread discussing psilocybin microdosing, so be aware of that and maybe not get excited that so many "people" are discussing it.
Dr. Damien P. Williams
…HUH. Long-COVID destroys synapses, and is a major contributor to the brainfog. https://www.nature.com/articles/s41380-022-01786-2
This goes some way to shining a light on the promising results they've been seeing in testing nicotine patches as treatment for long covid: nicotine effects synapse formation and receptivity (tests using patches because they don't habit-form and aren't, y'know, SMOKE [https://bioelecmed.biomedcentral.com/articles/10.1186/s42234-023-00104-7]).
But what's super interesting to me is that another thing that's also been shown to encourage synapse growth? Is psilocybin.
#psychology #counseling #socialwork #psychotherapy #research @psychotherapist @psychology @socialpsych @socialwork #Vaccines #COVID #longcovid #science #medicine #hospital #brainfog #sarscov2 #metformin #nicotine #nicotinepatch #psilocybin
Front of mind for Michael Pollan: psychedelics
As the #Vancouver #Police Department & #NorthVancouver #RCMP both carried out #raids on retail stores or warehousesfull of #psilocybin – or #MagicMushrooms – in recent weeks, Donna Benson was watching with interest.
The North Vancouver #clinical & #psychosocial #researcher has been taking note of the growing body of #evidence showing conclusive #therapeutic effects of psilocybin in treating people with #MentalIllnesses like #PTSD & major #DepressiveDisorder.
I am disappointed , especially because Microsoft wouldn't exist without the use of these medicines. :sadmsn:
"#PsychedelicAssisted #psychotherapy combines the psychology of talk therapy with the power of a #psychedelic experience. Researchers have described cases in which subjects report profound, personally transformative experiences after one six-hour session with the psychedelic substance #psilocybin, taken in conjunction with psychotherapy."
Western doctors and #psychedelics:
"One of my chronically depressed patients recently found a #psychoactive drug that works for him… He took some #psilocybin from a friend and experienced what he deemed a miraculous improvement in his mood. “It was like taking off a dark pair of sunglasses, everything suddenly seemed brighter.”
I don’t doubt my patient’s improvement. But I’m not convinced that his brief, oceanic experience was the source of the magic."
"If context is essential, the hallucinogenic experience itself might be necessary to open critical periods.
“The altered state invites all the different ways of thinking about things,” says Rachel Yehuda,a psychiatrist at MountSinai in NYCity. Her group is studying the use of #MDMA & #psilocybin in people with #PTSD, which the researchers think helps people to open up about traumatic experiences and address them in ways they normally couldn’t."
Hey my #psilocybin #shrooms peeps: after the second flush of my buddy’s crop of #GoldenTeacher mushrooms, a few “mutants” appeared and grew. They look like failed Golden Teacher genetic experiments, but they still grew and popped their veils.
The question is, are these safe or should I tell him to toss them?
Part of the solution to reducing the number of animals used in research could be to switch to using other species, like insects. I've just written a blog about that:
#Behavior #behavior #Porsolt #Danio #Dropsophila #OpenField #LightDark #ForcedSwimTest #Psilocybin #Psilocybe #zebrafish
This is an exciting step forward, and a brilliant example of how rongoā #Māori practitioners and western medical researchers can collaborate.
Cultivation licence granted for Psilocybe Weraroa, a variety of mushroom that contains #psilocybin. https://www.nzherald.co.nz/nz/first-medicinal-licence-grants-for-indigenous-magic-mushrooms-can-they-help-p-addicts/XDU5B5RNQFEBHOE5KGXNTINW2E/
I just finished watching HOW TO CHANGE YOUR MIND, the 2022 miniseries based on the book of the same name by Michael Pollan. It's streaming on Netflix and I found it excellent. Some truly powerful stories and a lot of fascinating information and history.
Also, my state was the first to decriminalize psilocybin and legalize its supervised use, which I believe was a good decision.
Day 3 of microdosing psilocybin. I have already had reduced depression, decreased anxiety and increased productivity. I’m starting to be interested in things again, which the depression had basically killed. My focus is also better, my thinking feels less chaotic and I am experiencing a decrease in racing thoughts. This isn’t to say I’m not still struggling, just that I am noticing improvements and am grateful for them. #Microdosing #Psilocybin #TreatmentResistantDepression #Depression
"People usually trip in scenic environments with their friends. That’s hard to replicate under scientific observation."
#Psilocybin has long been recognized as a classic #psychedelic substance and has recently been investigated for its potential to assist in the treatment of various #psychiatric disorders, primarily depression and addiction, through therapy supplemented with a high dose of psilocybin.
I’ve been looking into this for a while, but didn’t know of a reputable source to get them from locally until today. I also have a good friend who microdoses them and is knowledgeable about it, so we had a few chats about it. I’m taking my second dose today, so we’ll see how that goes. Desperate for any symptom relief after many years of suffering, to be honest. #TreatmentResistantDepression #Depression #Microdosing #Psilocybin #Shrooms
I didn't think it was practically possible to overdose on #psilocybin. I have consumed legendary quantities of #mushrooms (1oz over a 30 min period) in my youth, and never experienced anything close to death or incapacitation. Granted, I no longer existed in reality, but I was physically fine, and mentally back to normal after 10 hours. In this woman's case there must have been complications stemming from her paralysis. As far as I'm concerned, #shrooms are safe AF.
TITLE: Psilocybin‐assisted psychotherapy for treatment‐resistant
depression: Which psychotherapy?
From the abstract, looks like interpersonal psychotherapy and intensive
short-term dynamic psychotherapy are the most promising candidates.
I'll have to give this a full read later.
This might be of special interest to psychotherapists in and around
Washington, DC which has legalized psilocybin. Of course, it being
available recreationally is not the same as a therapeutic regime -- but
therapeutic clinics are emerging rapidly in the area.
*Psilocybin‐assisted psychotherapy for treatment‐resistant depression:
This article is from the NYU Information for Practice website which puts
out an extraordinary 400-500 quality posts per week! I have a robot
that posts all this at:
*Michael Reeder, LCPC
*Hygeia Counseling Services : Baltimore / Mt. Washington Village location*
#psychology #counseling #socialwork #psychotherapy #legal
@psychology @socialpsych @socialwork
@psychiatry #mentalhealth #psychiatry #healthcare
#drugassistedtherapy #psilocybin #lsd #shrooms #magicmushrooms
NYU Information for Practice puts out 400-500 good quality health-related research posts per week but its too much for many people, so that bot is limited to just subscribers. You can subscribe at @PsychResearchBot
This is a must from #PBS #OPB #ThinkOutLoud for all those interested in #plant #plants #therapy #planttherapy #healing via a #mushroom #mushrooms #shroom #shrooms #trip...
And all those #ageist individuals who's own fear of growing #old makes them #prejudice against the #elderly....
At eighty-eight years #young #VivianAnderson is more lucid, open minded and forward thinking than most people half her #age!
I microdosed magic mushrooms for about 2.5 years on and off. I also marcodosed sporadically.
It has helped my mental health more than I ever imagined.
🍄 are helping everyday people like me get their life back.
We require even more of a shift in narrative around psychedelics, and one way to do that is to talk about it.
🍄 Evidence Grows for Psilocybin as a Treatment for Depression
A research review published this month in the Journal of Psychiatric Practice shows that a growing body of evidence suggests that psilocybin could be an effective treatment for depression
"A Single Dose of Magic Mushroom Psychedelic Can Ease Major Depression, Study Finds"
"A single dose of psilocybin can lead to a 'rapid, robust, and sustained reduction' in symptoms of severe depression when taken in conjunction with psychotherapy, according to a new study."
He looks like the kinda fella who would run a magic mushroom church, he's doing great. 🍄
"Hodges said his church, which has nearly 92,000 members, is accepting new members only at its original location in Oakland. He previously told SFGATE that he was willing to go to jail to protect his right to practice his religion."
What a lad.
"A senior Metropolitan Police officer who wrote the force's anti-drugs strategy took LSD and magic mushrooms while off duty and smoked cannabis before work, a tribunal has heard."
This is quite a wonderful use of comics-style informational graphics by the State of Oregon regarding a new process to provide access to psilocybin for mental health therapeutic use. #comics #infographic #psilocybin https://audmcname.com/assets/neuro_prologue.pdf The art’s by Audra McNamee, can’t find them in the Fediverse though.
Australia has become the first nation to approve prescribing of #MDMA and #psilocybin for #PTSD or #depression, in combination with psychotherapy. But experts say the move is premature and based on inadequate evidence.
#psychedelics #MentalHealth #Psychiatry #psychotherapy
Researchers are concerned about lack of guidance for use & the fact that they don't have a way of identifying patients likely to react badly to the drugs.
Safer Forms of Psilocybin Assessed in Preclinical Study
Magic mushrooms seem to have a strange effect on #color #blindness https://www.sciencealert.com/magic-mushrooms-seem-to-have-a-strange-effect-on-color-blindness #psilocybin
"The UK is “still in the dark ages when it comes to the positive benefits of psilocybin”, SNP MP Owen Thompson has said.
A cross-party group of politicians was told that psilocybin – the active ingredient in magic mushrooms – can be "life-saving" for people struggling with mental health problems."
There's some evidence it can help with alcohol issues too.
Apropos of nothing.
Stay safe and have fun out there, psychonauts! 🍄
A legal high won't come cheap in Or
#News #Drugs #psilocybin #Oregon
"It beat the pants off the antidepressant!" Says my wife. #Psilocybin
[Edit: I meant to thread this: https://social.ridetrans.it/@Andres4NY/110306566647624086]
"Former Home Secretary Priti Patel has unveiled a memorial bench to four swans thought to have been killed in a catapult attack...
"...After the unveiling, Ms Patel said she was "moved" to be part of the ceremony..."
Trial to Test Low-Dose Psilocybin for Mental Distress
»The theory suggests that these hominids began following herds of animals as a source of food. Psilocybe cubensis mushrooms thrive in the droppings of these herds. It stands to reason that these early hominids would have come across, & subsequently consumed them. The theory is that the transcendental power of these mushrooms being eaten over & o. again was the catalyst for this massive leap in brain power – Like a software update for the organic computer that became the human brain.« #Psilocybin
Psychedelics may treat depression by invading brain cells
"#LSD und #Psilocybin aus "#MagicMushrooms" sind Drogen, strikt verbotene Substanzen. Und doch könnte es sein, dass sie bald als Medikamente zugelassen werden - gegen #Depressionen und Süchte. Nach ihrer Entdeckung durch die Hippiebewegung verschwanden die Substanzen aus der Forschung. Aber inzwischen untersuchen Wissenschaftler*innen auf der ganzen Welt deren Heilungspotenzial."
The Divine Assembly’s members use shrooms to commune directly with the “divine.” It’s one of a growing number of churches that worship using drugs.
#News #Drugs #Utah #psychedelicmushrooms #psilocybin #ReligiousFreedom #saltlakecity
#introduction eleph.social #admin. Happily married since 2017. Electrical Technology (Construction) AAS, #ComputerScience BS. #Dogs saved my life. I'm #queer and #NeuroSpicy. I like #FOSS, #Emacs, #Spacemacs, #EvilMode, #OrgMode, #PKM, #Rust, #Horror, #CrustPunk, #RABM, #Cannabis, #Guitars, #Mathematics, #Electronics, #RetroComputing, #Android, #Psilocybin. Want #solarpunk #homesteading but have limited energy cuz chronic #depression. #Nihilism but #Radical #compassion. #Possums! #Pacifism
On Jan. 1, Oregon became the first state to allow adult use of #psilocybin “magic” mushrooms which has shown significant promise for treating severe depression, post-traumatic stress disorder and end-of-life anxiety among the terminally ill, among other mental health conditions.
We've previously reported on the critical need for those historically left out of research, women and people of color, to be included in studies of it's use and benefits
𝗣𝘀𝗶𝗹𝗼𝗰𝘆𝗯𝗶𝗻, 𝗼𝘁𝗵𝗲𝗿 𝗽𝘀𝘆𝗰𝗵𝗲𝗱𝗲𝗹𝗶𝗰𝘀, 𝗼𝗳𝗳𝗶𝗰𝗶𝗮𝗹𝗹𝘆 𝗱𝗲𝗰𝗿𝗶𝗺𝗶𝗻𝗮𝗹𝗶𝘇𝗲𝗱 𝗶𝗻 𝗖𝗼𝗹𝗼𝗿𝗮𝗱𝗼
Governor signs off on Prop 122 which passed by voters Nov. 8.Coloradoans 21+ can now posess, ingest and cultivate mushrooms, DMT, ibogaine and mescaline at home without criminal penalty.
I really like microdosing mushrooms. I really like Mastodon. And I really like Jonah Hill’s documentary Stutz. Today, they converged so I wrote about it.
I am Bi man from the Seattle area and #TwitterRefugee hoping to explore many of my interests here on Mastodon. For the near future I am just going to lurk and learn while I RTFM so I can learn to use Mastodon as well as see how the culture develops.
The reason I state I am Bi man at the beginning of this post is to help raise awareness of the #Bisexual community which is often misrepresented in the media and news. Obviously #Bisexuality and #LGBTQ issues and news are interests I will follow and contribute to here on Mastodon.
Other interests include:
#robotics #IoT, #Python #AI
#meditation #sleepdisorders #stressmanagement #ASMR
#cannabis #medicalmarijuana #psilocybin #accessibility #disability #ageism #sciencefiction #cats #crows #weather #astronomy #spaceexploration #oceanography #climatechange #teraforming #greenenergy
That's a long and rambling list, and I am sure there is more, but that's the best I can come up with for now.
This is my longest post for now, and I just used my first 1000 characters. Now that's something to toot about and not tweet about.