Masthash

#lung

Giuseppe Michieli
1 week ago

''After infection of #mice with #H11N9 virus at 103 EID50 dose, the virus was able to replicate in #lung without prior #adaptation, though the replication of the virus was limited. And virus was also detected in other organs including nasal #turbinate, #brain, and #colon. This was the first detection of H11N9 virus in nervous and digestive system of mice''

IMPACTT Microbiome
1 week ago

#HavingIMPACTT2023 Plenary Speaker Profile: Meet Dr. Christina Thornton, adult Respirologist and Assistant Professor at the University of Calgary who will speak about the lung microbiome in suppurative disease

#microbiome #lung #disease #symposium #conference

Plenary Speaker Profile for Christina Thornton, MD/PhD: Christina Thornton, MD PhD PRCPC is an adult Respirologist and Assistant Professor at the University of Calgary, specializing in cystic fibrosis and bronchiectasis. Her research interests include the role of polymicrobial infections at times of clinical stability and pulmonary exacerbation in suppurative lung disease, and she aims to develop a Canadian Bronchiectasis database to better understand the role of the lung microbiome in these patients.
Scientific Frontline
1 month ago

#Immune checkpoint blockade therapies have been revolutionary in the treatment of some #cancer types, emerging as one of the most promising #treatments for diseases such as #melanoma, #colon cancer, and non-small cell #lung cancer.
#Medical #Pharmaceutical #sflorg
https://www.sflorg.com/2023/05/med05132301.html

Gabriele Pollara
3 months ago

Not a new paper, but still a neat demonstration PCP on the rise due to iatrogenic / disease immunosuppression, not #hiv

#IDMastodon #pcp #pulmonary #disease #Lung

https://www.sciencedirect.com/science/article/pii/S266677622200093X?via%3Dihub

Auscandoc
3 months ago

"We saw this same pattern across all human #COVID lung samples," Wernig said. As with other #lung infections, the initial #COVID19 infection in the lungs kicked off an #inflammatory process. In the case of #LongCovid patients, however, the #immune dysfunction keeps going long after the virus is gone -- similar to what happens in chronic #PulmonaryFibrosis.โ€

https://scopeblog.stanford.edu/2023/03/17/runaway-immune-reactions-cause-long-covid-breathing-problems/

Tilo Winkler
3 months ago

๐™๐™€๐™Ž๐™€๐˜ผ๐™๐˜พ๐™ƒ ๐™๐˜ผ๐™‡๐™† // Dr. Sean Fain: Insights from Pulmonary MRI and CT Imaging in Asthma - March 29, 2023 @ 5:30pm EDT
Details at > https://anesthesia.massgeneral.org/RHH/RHH.htm

#science #talk #lung #respiratory #research #pulmonary #imaging #asthma #MRI #PET

MGH - Anesthesia
Research Happy Hour
UPCOMING - Talk & Discussion
Sean Fain: Insights from Pulmonary MRI and CT Imaging in Asthma - March 29, 2023 @ 5:30pm EDT
Details at: https://anesthesia.massgeneral.org/RHH/RHH.htm
Giuseppe Michieli
3 months ago

Divalent #siRNAs are bioavailable in the #lung and efficiently block #SARS-CoV-2 infection https://www.pnas.org/doi/abs/10.1073/pnas.2219523120?af=R

Leibniz-HKI
3 months ago

The fungus ๐˜ˆ๐˜ด๐˜ฑ๐˜ฆ๐˜ณ๐˜จ๐˜ช๐˜ญ๐˜ญ๐˜ถ๐˜ด ๐˜ง๐˜ถ๐˜ฎ๐˜ช๐˜จ๐˜ข๐˜ต๐˜ถ๐˜ด hijacks a human protein to escape intracellular killing in lung surface cells. It redirects their phagosomes to a non-degradative pathway: https://www.leibniz-hki.de/en/press-release/fungal-spores-hijack-lung-cells.html
@dfg_public
@unijena

Direct link to the article in Cell Host & Microbe:
https://doi.org/10.1016/j.chom.2023.02.002

#Microorganisms #fungalinfections #lung #scicomm

Andy
3 months ago

#Lung #Cancer Rates Are Soaring Among Unlikely Groups - need to be on the lookout for this especially in my #fcp role in #primarycare - just ask yourself do the #symptoms fit for a #mechanical pattern or could it be something else? @physiotherapy https://flip.it/hksaXQ

25% of #COVID19 patients have lasting reduction in #lung function

"findings reported that at 12 months of follow-up, one-fourth of the participants continued to have impaired pulmonary function, with mild, moderate, and severe SARS-CoV-2 infections accounting for 11%, 22%, and 48% of these cases, respectively."

https://www.news-medical.net/news/20230228/2525-of-COVID-19-patients-have-lasting-reduction-in-lung-function.aspx

One-Fourth of COVID-19 Patients Have an Impaired Pulmonary Function after 12 Months of Illness Onset

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4366836

#sarscov2 #Sars2

David Hill
3 months ago

I just emailed my Congressional Representatives asking them to adequately fund lung health programs. You can too! https://a.lung.org/XxDfSep or text LungHealthPrograms to 52886 to take action. #Lunghealth #pulmonary #Lung

Alan Kotok
3 months ago

mRNA Aerosol Delivered to Lungs to Treat Pneumonia

Messenger #RNA, inhaled from an #aerosol #spray, is shown in lab rats with #pneumonia to reduce #inflammation, improve #lung functions, and protect against further #infections.

https://sciencebusiness.technewslit.com/?p=44497

#News #Science #Business #Collaboration #mRNA #NucleicAcid #ARDS #Preclinical #Biotechnology #Chemistry #Nanotechnology #Ireland

Inspecting lung X-rays

#Chest #CT shows #lung abnormalities two years after #COVID

Chest CT revealed persistent lung abnormalities in patients two years after #COVID19, according to a study published in Radiology. This is the first research paper with two-year follow-up data on #COVID19 lung effects.

Prospective study, n=144

CT Abnormalities:
6 mos: 54%
24 mos: 39%

Respiratory issues:
6 mos: 30%
24 mos: 22%

https://medicalxpress.com/news/2023-02-chest-ct-lung-abnormalities-years.html

https://pubs.rsna.org/doi/10.1148/radiol.222888

#sarscov2 #SARS2

Giuseppe Michieli
4 months ago

Inquilinus limosus #Bacteremia in #Lung #Transplant Recipient after #SARS-CoV-2 Infection https://wwwnc.cdc.gov/eid/article/29/3/22-1564_article

LocalHealthGuide
4 months ago

A nagging cough can hang on for weeks or months following a respiratory illness โ€“ and there is precious little you can do about it.

But while a relentless cough after a viral infection can be frustrating and worrisome, but in most cases, coughs resolve over time.

https://bit.ly/3YwCJrr

#cough #asthma #lung #cancer

Man coughing into his fist.
irtapil
4 months ago

#intoduction

I'm extremely curious & extremely easily distracted.

I dropped out of a #PhD on the #evolution of #lung #pathogens somewhere in the late 2010s (it's ambiguous exactly when)

I'm an #English speaker trying to learn an unfeasible number of #Languages including #Russian #Hindi #Farsi #Arabic #German and too many others to make any progress on, but I'm having fun trying.

I joined on a very small server @irtapil@sauropods.win and then found space on here, currently I plan to keep both profiles.

Auscandoc
4 months ago

โ€œ#UniversityofSydney scientists have discovered a #protein in the #lung that blocks #SARSCoV2 infection and forms a natural protective barrier in the human body.

This protein, the leucine-rich repeat-containing protein 15 (#LRRC15), is an inbuilt receptor that binds the SARS-CoV-2 virus without passing on the infection.โ€

https://www.sydney.edu.au/news-opinion/news/2023/02/10/scientists-discover-receptor-that-blocks-covid-19-infection.html

LocalHealthGuide
4 months ago

Lung cancer rates have risen among nonsmokers and young women โ€” why?

The American Lung Association reports that while lung cancer rates have risen by 79% for women over the last 44 years, they decreased by 43% for men. And for the first time in history, there are more young women than men diagnosed with lung cancer.

https://bit.ly/40Gyknh

#lung #cancer #womenshealth #women

Image from a low-dose CT scan. Such scans can help with early detection of lung cancer. In this image, the tumor is the white nodule in the upper right corner of the black space. Atlas of Pulmonary Pathology/Flickr, CC BY-SA
Tilo Winkler
4 months ago

@albertocairo
1/N thread - (writing a meaningful short answer required more time than a long one)

First principle for scientific papers: readability and explorability of data must have priority over aesthetic preferences. Graphic design should support the readability and clarity of the data rather than dominate it. #dataviz must aid the communication of unique, potentially complex findings among experts.

An example from: https://doi.org/10.2967/jnumed.120.245977 #PET #imaging #pulmonary #perfusion #HIV #lung

Figure 3 of the cited paper
Tilo Winkler
4 months ago

It was a great pleasure to host our department's first Research Happy Hour in 2023.

Excellent talk by Dr. Sydney Montesi about Molecular PET Imaging of Pulmonary Fibrosis.

#pulmonary #PET #CT #imaging #lung #respiratory #disease

announcement of the website
Wonderful
5 months ago

In both men and women worldwide, lung cancer (small cell and non-small cell) is the second most common cancer. Thus, many scientists and #research organisations are working to improve #lung #cancer detection and #treatment.

Based out of Liege, a city in Belgium, DeuterOncology, is a clinical-stage drug development company working to advance in this field. Now the Belgian #startup has raised โ‚ฌ5.65M in a Series A #funding round

https://techfundingnews.com/belgian-biotech-by-pharma-expert-gets-e5-65m-capital-injection-to-treat-lung-cancer/

Scientific Frontline
5 months ago

#Lung #cancer is the No. 1 deadliest cancer in the world, resulting in 1.7 million deaths worldwide in 2020, killing more people than the next three deadliest cancers combined.
#AI #ArtificialIntelligence #Medical #sflorg
https://www.sflorg.com/2023/01/ai01202301.html

Auscandoc
5 months ago

โ€œCanadians diagnosed with most common #cancers are more likely to survive the disease if they detect it at an earlier stage, according to a new report from #StatisticsCanada.

It looked at cases of the most commonly diagnosed cancers in Canada between 2010 and 2017, including #lung, #breast, #prostate, #colon and rectal cancer โ€” all of which collectively make up almost half of all diagnosed cancer cases in Canada.โ€

https://globalnews.ca/news/9418705/cancer-survival-rates-canada/

Scientific Frontline
5 months ago

The powerful new substance could become the basis for #antitumor drugs because it affects the #pathology that leads to the development of malignant #tumors, such as #cancer of the #breast, #lung, #prostate, and #lymph nodes.
#Chemistry #Medical #sflorg
https://www.sflorg.com/2023/01/chm01172301.html

Alan Kotok
5 months ago

Trial to Assess At-Home Asthma Lung Function Tests

A clinical trial is set to begin that compares monitoring of #lung functions in people with #asthma using portable #ultrasound and mobile app at home to conventional tests in a clinic.

https://sciencebusiness.technewslit.com/?p=44341

#News #Science #Business #ClinicalTrial #Spirometry #Software #CloudComputing #Algorithms #DigitalBiomarker #Smartphone #LABA

Adult with asthma inhaler
Giuseppe Michieli
5 months ago

Parenchymal #lung #abnormalities following #hospitalisation for #COVID19 and viral pneumonitis: a systematic review and meta-analysis http://thorax.bmj.com/cgi/content/short/78/2/191?rss=1

LocalHealthGuide
5 months ago

ARE GAS STOVES BAD FOR YOUR HEALTH?

Why the government is considering new safety regulations.

"One of the main air pollutants commonly associated with using gas stoves is nitrogen dioxide. Nitrogen dioxide exposures in homes have been associated with more severe asthma and increased use of rescue inhalers in children. This gas can also affect asthmatic adults, and it contributes to both the development and exacerbation of chronic obstructive pulmonary disease." https://bit.ly/3QworUy #lung

Blue flames from a gas burner.
Science News
5 months ago

This story sparked a ton of questions from Science News readers. So we dug deeper: https://www.sciencenews.org/article/fungi-lung-infections-questions-symptoms-treatment

#fungi #lung #infection #symptoms #treatment

irtapillarsaurus
5 months ago

belated #into post

Extremely curious and extremely easily distracted,

Dropped out of a #PhD on the #evolution of #lung #pathogens somewhere in the latter half of the 2010s (it is ambiguous when)

#English speaker trying to learn an unfeasible number of #Languages including #German #Russian #Hindi #Farsi #Arabic and too many others to make any progress on, but I'm having fun trying.

I'm also on one of the main servers @irtapil@mastodon.online but I've decided to keep both for now.

Mycotropic
5 months ago

I don't know whether this applies to anyone else in the world other than me but I've found that I suppress my cough reflex in public these days. #COVID of course and that's a problem since respiratory transmission of any virus isn't optimal but as I understand it chronic suppression of a cough can be problematic for some people; #LadyWindermereSyndrome (to coin a hashtag potentially) https://radiopaedia.org/articles/lady-windermere-syndrome?lang=us I wonder whether this is happening...

#pulmonary #lung #epidemiology #respiratory

Scientific Frontline
5 months ago

Adults who stay well-#hydrated appear to be #healthier, develop fewer #chronic conditions, such as #heart and #lung #disease, and live longer than those who may not get sufficient fluids
#Medical #Biology #Water #sflorg
https://www.sflorg.com/2023/01/med01032301.html

h/t DrGrahamLJ

The lung disease of #COVID19 is not a conventional respiratory 'pneumonia'. It is a 'pulmonary vasculopathy' - a disease of the lung blood vessels.

#COVID19 #Lung Disease: A #Pulmonary #Vasculopathy

https://youtu.be/2jROYLwUK20

#SARS2 #sarscov2 #COVID #vasculitis

Tilo Winkler
6 months ago

My new editorial about #airway #remodeling in #asthma is finally out. A surprising and fascinating aspect of #ComplexSystems behavior is that multiple mechanisms can be involved in shifting a #TippingPoint. In asthma, there are several distinct mechanisms of airway remodeling, but they converge in a combined effect of shifting the tipping point for severe asthma attacks: https://doi.org/jq7c https://atm.amegroups.com/article/view/104046/html

#TippingPoints #complexity #emergence #lung #respiratory #research #PIBLabs

Header section of the editorial
Airway narrowing during a simulated asthma attack in a computational model of bronchoconstriction in an airway tree. Initially, airway behavior is homogeneous until the critical point in bronchoconstriction is reached. Beyond that point, positive feedback leads to the emergence of separated clusters of airwaysโ€“โ€”also referred to as phase separationโ€”resulting in regions with ventilation defects (VDefs).
Tilo Winkler
6 months ago

Very exicted to share that our #PET #imaging paper in #PulmonaryHypertension #PAH is out: https://doi.org/10.1186/s12931-022-02239-8
Many thanks to our great team at @MGHanesthesia@twitter.com @MGH_PCCM@twitter.com

CONCLUSIONS: Perfusion imaging during O2โ€‰+โ€‰iNO showed a significant difference in the heterogeneity associated with the vertical gradient in perfusion, distinguishing in this small cohort study PAH subjects from controls.

#lung #respiratory #research #pulmonary #perfusion #circulation #PETCT #PIBLabs

header part of the webpage
data excerpt: total heterogeneity and heterogeneity associated with the vertical gradient in perfusion showing during O2+iNO discrimination between PAH and controls
Alan Kotok
6 months ago

A clinical trial is underway testing a mobile #app designed to help people with a serious #lung disorder manage #anxiety that often accompanies the disease. https://sciencebusiness.technewslit.com/?p=44184 #Science #Business #ClinicalTrial #MentalHealth #PulmonaryFibrosis #Smartphone #Collaboration #CBT #Sweden

Almee smartphone app
Tilo Winkler
6 months ago

#introduction: I am a biomedical engineer at the ๐—ฃ๐˜‚๐—น๐—บ๐—ผ๐—ป๐—ฎ๐—ฟ๐˜† ๐—œ๐—บ๐—ฎ๐—ด๐—ถ๐—ป๐—ด ๐—ฎ๐—ป๐—ฑ ๐—•๐—ถ๐—ผ๐—ฒ๐—ป๐—ด๐—ถ๐—ป๐—ฒ๐—ฒ๐—ฟ๐—ถ๐—ป๐—ด ๐—Ÿ๐—ฎ๐—ฏ๐—ผ๐—ฟ๐—ฎ๐˜๐—ผ๐—ฟ๐—ถ๐—ฒ๐˜€ (๐—ฃ๐—œ๐—•๐—Ÿ) at Massachusetts General Hospital in Boston, MA, US. My research focuses on pulmonary imaging, computational modeling, data analysis, and scientific data visualization. Learn more at: https://pibl.mgh.harvard.edu/T.Winkler_PI-profile.html

Main interests: #PET #imaging #lung #pulmonary #perfusion #ventilation #respiratory #physiology #asthma #modeling #ComplexSystems #complexity #emergence #dataviz

#Brexit has worsened shortage of #NHS #doctors, analysis shows

More than 4,000 European medics have chosen not to work in NHS since Britain left EU, data reveals

Four major types of medical specialities impacted โ€“ #anaesthetics, #children, #psychiatry, and #heart and #lung treatment

https://www.theguardian.com/society/2022/nov/27/brexit-worsened-shortage-nhs-doctors-eu

Doctors
jobRxiv
6 months ago

Postdoc - Yale University - Vascular or Lung Biology @GreifLab

Come join the Greif lab to investigate #cardiovascular or #lung biology in a dynamic, collaborative and fun environment @Yale @YaleCVRC @YaleGenetics.

https://jobrxiv.org/job/yale-university-27778-postdoc-yale-university-vascular-or-lung-biology/?feed_id=30147
#Science...
https://jobrxiv.org/job/yale-university-27778-postdoc-yale-university-vascular-or-lung-biology/?feed_id=30147

Scientific Frontline
7 months ago

#Fungi in the #soil cause a significant number of serious #lung #infections in 48 out of 50 states and the District of Columbia, including many areas long thought to be free of deadly environmental fungi, according to a study by researchers
#Medical #Environmental #sflorg
https://www.sflorg.com/2022/11/med11192202_01435247395.html

The Wise ET
2 years ago

#FAKE #FEAR OF NON-EXISTING "#CORONAVIRUS" IS CAUSING SEVERE DAMAGE TO THE #PLANET, #CHILDREN, ADULTS, ECONOMIES, COUNTRIES

>>Schools and other facilities adopted them due to fears surrounding the #Chinese "#virus", but this rushed, reactionary response is now causing other problems in the form of #lung #damage.

>>โ€œWe are now verifying whether any of these particular #masks remain in our schools and centers,โ€ reads a letter sent by the Lester B. Pearson school board to the parents of all exposed children.

ยฎโˆ† โˆ‘ โ€ข โ–ฒ โ™  โ—Š โ™ฃ โ™ฆ โ— โ™ฆ โ™ฅ โˆ‘ โˆ†ยฎ

stefania maurizi [bot]
2 years ago

I officially asked to the UK authorities why they keep Julian #Assange in a cell freezing,during a pandemic, and also considering he has a #lung problem (on which I have reported as early as 2012). Waiting for a reply https://twitter.com/SMaurizi/status/1337436775451652099 #UK

--
Full-List of bots: https://joejoe.github.io/mastodon

O=C=O
3 years ago

Burning #FossilFuels Made #Coronavirus Death Rate Worse, and Kills 200K Americans Per YEAR, Not to Mention #GlobalHeating

Air #pollution, producing medical conditions such as #asthma and other #lung #problems as well as #heart #disease, is responsible for some of the thousands of coronavirus deaths in the #US.
Trumpโ€™s response to the #pandemic has been to abolish clean air regulation, which is exactly the opposite of what we should be doing.

https://www.commondreams.org/views/2020/04/12/burning-fossil-fuels-made-coronavirus-death-rate-worse-and-kills-200k-americans

#ClimateCrisis #Oil #Gas

A gas flare is seen at an oil well site on outside Williston, North Dakota. (Photo: Andrew Burton/Getty Images)