Masthash

#neuroscience

#Researchers propose that a taste for #fermented morsels may have triggered a surprising jump in the growth rate of our ancestors' #brains.

In fact, a shift from a #RawDiet to one that included #food items already partially broken down by #microbes may have been a crucial event in our brain's #evolution, according to a perspective #study by evolutionary #neuroscientist Katherine Bryant of Aix-Marseille University in France and two US colleagues.

https://www.sciencealert.com/preparing-food-with-microbes-could-be-why-we-now-have-such-impressive-brains

#Science #neuroscience

karafuto
58 minutes ago

This year I finished one of the most fascinating projects I ever worked on.

Together with a team of researchers from the molecular neurodegeneration department at Amsterdam UMC we came up with a visual and interactive way to present their latest paper on tau protein aggregation and its effect on astrocytes.

🧵
#neuroscience #dementia #alzheimers #science #scicomm #design #UI #gamedev #ScienceMastodon #visualStorytelling #astrocytes

a grid from the first level of the game, made out of boxes with tau protein symbols inside of them, some tau filled with white color, some outlined. the goal of the first level is to place white tau proteins in the boxes so that there are no outlined symbols remain

PTSD patients’ brains work differently when recalling traumatic experiences. Researchers say that 'the brain does not treat traumatic memories as regular memories, or perhaps even as memories at all.'

https://www.popsci.com/health/ptsd-memories-look-different/

#neuroscience

The vOICe vision
6 hours ago

Visual working memories are abstractions of percepts https://www.biorxiv.org/content/10.1101/2023.12.01.569634v1 Does this not depend on retrieval delay? 12s is a rather long time for image retention. #neuroscience

Population receptive field mapping, trial design, and stimuli generation schema.
The vOICe vision
13 hours ago

(flashback, 2008) A what/where visual-to-auditory sensory substitution fMRI study: can blind and sighted hear shapes and locations in the visual cortex? https://web.archive.org/web/20140812030845/http://www.perceptionweb.com/abstract.cgi?id=v080153 (web archive, ECVP 2008); #neuroscience

The vOICe vision
22 hours ago

Induction of excitatory brain state governs plastic functional changes in visual cortical topology https://link.springer.com/article/10.1007/s00429-023-02730-y Principles of #plasticity in the #adult #visual #cortex, noninvasive stimulation methods; #neuroscience

Snowshadow
23 hours ago

A Neural Blueprint for Depression
Source: SfN

In studies that examine the depressed brain, researchers were able to identify specific genes, molecules, brain regions, and cognitive features that are associated with the disorder.

#neurology #neuroscience #psychology #biology #science #brain #sciencenews #news

https://neurosciencenews.com/depression-blueprint-25199/

Snowshadow
23 hours ago

Peptide PACAP’s Key Role in Alcohol Addiction
Source: Boston University

Alcohol is the most common addictive substance in the world. Every year in the U.S. excessive alcohol use costs $249 billion and causes approximately 88,000 deaths, as well as various chronic diseases and social issues.

#genetics #psychology #neuroscience #science #social #neuroscience

https://neurosciencenews.com/pacap-alcohol-addiction-25298/

Snowshadow
23 hours ago

Babies Learn Language Best Through Sing-Song Speech, Not Phonetics
Source: University of Cambridge

Parents should speak to their babies using sing-song speech, like nursery rhymes, as soon as possible, say researchers. That’s because babies learn languages from rhythmic information, not phonetic information, in their first months.

#neuroscience #parenting #science #language #baby #speech #news

https://neurosciencenews.com/language-learning-neurodevelopment-25297/

Snowshadow
23 hours ago

How Imagination Fuels Empathy and Prosocial Behavior

Source: McGill University

"In a world grappling with deep-seated division and social upheaval, empathy has become more critical than ever."

#psychology #neuroscience #science #behaviour #socialjustice #social

https://neurosciencenews.com/empathy-imagination-25302/

Fabrizio Musacchio
1 day ago

📢 The brand new AI Institute #ARNI (ARtificial + Natural Intelligence) is hiring postdocs to work at the intersection of #AI+#neuro, at Columbia University:

Info: https://arni-institute.org
Apply: https://apply.interfolio.com/125533
#neuroscience #CompNeuro #JobAlert

Jeremy Mallin
1 day ago

Columbia University Irving Medical Center: Children with #Autism Have Extra Synapses in Brain

#neuroscience #neurology
https://www.cuimc.columbia.edu/news/children-autism-have-extra-synapses-brain

Max-auf-der-Rax
1 day ago

@molosovsky

new study „focuses on two aspects: personal distress and compassionate concern. The study reveals that vividly imagining someone else’s problems increases personal distress, motivating individuals to offer help. These findings break new ground in understanding the connection between mental experiences and actions, shedding light on why certain situations and individuals elicit more empathy than others“
https://neurosciencenews.com/empathy-imagination-25302/
#GroßraumPhantastik #fiction #neuroscience #imagination

Jerzy Jarmasz
2 days ago

This is either complete bullshit (my suspicion) or utter depravity that needs to be stopped in it's tracks. Having people work in their sleep, ferchrissakes... #LucidDreaming #Neuroscience #coding https://fortune.com/2023/11/30/lucid-dream-startup-prophetic-headset-prepare-meetings-while-sleeping/

Joel Snyder
2 days ago

Please share this job ad for full-time non-tenure track #teaching intensive faculty in the area of #neuroscience.

UNLV just in the past 10 years has started a neuroscience minor, a neuroscience Ph.D. program, and in the next year or two will have a neuroscience B.S. degree and a new research-intensive MRI facility. Neuroscience is all over campus now, and continues to grow. So please consider applying.

https://nshe.wd1.myworkdayjobs.com/UNLV-External/job/UNLV1-Main-Campus-Las-Vegas/Assistant-Professor-in-Residence--Neuroscience--College-of-Liberal-Arts--R0139794-_R0139794

If pulling an all-nighter, don't follow with an important decision, suggests a new brain imaging study. Researchers found a 24-hour period of sleep deprivation significantly impacted individuals' decision-making processes by dampening neural responses to the outcomes of their choices.

https://www.uottawa.ca/about-us/media/news-all/pulling-all-nighter-dont-follow-important-decision

#neuroscience

The vOICe vision
2 days ago

More than expected: extracellular waveforms and functional responses in monkey LGN https://www.biorxiv.org/content/10.1101/2023.11.22.568065v1- "key populations in the LGN may have been missed", so why not include auditory stimuli in addition to visual stimuli to identify any previously overlooked signals? #neuroscience

BugHunterCat
2 days ago

"If the brain were so simple that we could understand it, we would be so simple that we would not understand it."

Lyall Watson

#neuroscience #actuallyautistic #bipolar #brain

Brains
2 days ago

How well can we measure, map, decode, and interpret brain activity? It depends on lots of factors. Dr. @russpoldrack explains in four short videos:

1. Measuring Brain Function
2. Mapping Mind to Brain
3. Brain Decoding
4. Interpreting Human Neuroscience Data

https://philosophyofbrains.com/2023/12/01/four-videos-about-neurometrics-and-brain-data-dr-russ-poldrack.aspx

This is the 6th of 7 sets of videos from “A Beginner’s Guide To Neural Mechanisms”.

#neuroscience #neurometrics #modeling #decoding #psychometrics #psychophysics #engineering #physics #biology #chemistry

Snowshadow
2 days ago

Anthrobots: Tiny Biobots From Human Cells Heal Neurons

"The researchers found that not only could the cells create new multicellular shapes, but they could move in different ways over a surface of human neurons grown in a lab dish and encourage new growth to fill in gaps caused
by scratching the layer of cells."
#neuroscience #science #bots #anthrobots #biology #research #news
https://neurosciencenews.com/anthrobots-cell-robot-neuron-healing-25296/

Snowshadow
2 days ago

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

“Understanding the complex world of RNA is a rapidly emerging area of neuroscience research, where we are constantly learning more about how different classes of RNA control the communication between and within brain cells,” Professor Bredy said.

#neuroscience #ptsd #rna
#genetics #psychology #science #mentalhealth #news

https://neurosciencenews.com/rna-fear-memory-25295/

Robert Roy Britt
2 days ago

#GeorgeSantos made his own bed, a bed of lies. But why would he lie so blatantly? And why do other powerful people get away with obvious and harmful lies?

My recent deep dive on the #psychology and #neuroscience of #lying explains the behavior of Santos and other big liars, whose pants rarely end up catching fire, as Santos' did. The nut:

Big, dehumanizing lies are destabilizing society. So why do powerful people spew such BS? And why do people believe them?

https://medium.com/wise-well/lies-damn-lies-and-total-bullshit-d8327df5dabd

Manlio De Domenico
2 days ago

#ComplexityThoughts issue #20 is out: this time we cover from #ComplexSystems foundations to #BioInspiredComputing #EvolutionaryBiology #ArtificialIntelligence #Neuroscience #Epidemiology

Unraveling complexity: building knowledge, one paper at a time!
Not yet subscribed? It's never too late, and it's 100% free.

https://manlius.substack.com/p/complexity-thoughts-issue-20

This #ComplexityThoughts drawn by an AI 👇

T. T. Perry
2 days ago

New neuroscience research upends traditional theories of early language learning in babies

The findings challenge traditional theories of language acquisition that emphasize the rapid learning of phonetic elements. Instead, the study suggests that the individual sounds of speech are not processed reliably until around seven months, and the addition of these sounds into language is a gradual process.

https://www.psypost.org/2023/12/new-neuroscience-research-upends-traditional-theories-of-early-language-learning-in-babies-214800

#Auditory #Language #Babies #Neuroscience #SLHS

Moritz Negwer
2 days ago

Developmental mouse brain + neuron atlases, from Yongsoo Kim's lab. This is going to be such a useful resource :)

"Here, we create high-resolution 3D atlases of the early postnatal mouse brain, using Allen CCFv3 anatomical labels, at postnatal days (P) 4, 6, 8, 10, 12, and 14, and determine the volumetric growth of different brain regions."

epDevAtlas: Mapping GABAergic cells and microglia in postnatal mouse brains
Liwang et al., preprint at biorxiv 2023
https://doi.org/10.1101/2023.11.24.568585

#neuroscience

Jonathan Z Simon
2 days ago

#neuroscience #paperThread New paper in PNAS by recent PhD Dushyanthi Karunathilake! https://doi.org/10.1073/pnas.2309166120
MEG responses from continuous speech listening lock to various stimulus features: acoustic, phonemic, lexical, & semantic. Could they provide an objective measure of when degraded speech is perceived as actually intelligible? This would give insight as to how the brain turns speech into language, and be a treasure mine for clinical populations ill-suited for behavioral testing. 1/5

Brain Study Suggests Traumatic Memories Are Processed as Present Experience

https://www.nytimes.com/2023/11/30/health/ptsd-memories-brain-trauma.html

#neuroscience

Gnôsis - Alexandre MARTIN
2 days ago

Lower socioeconomic status ‘triples risk of early-onset dementia’ - People from less privileged background at greater risk of developing condition under age of 65, finds new study based on UK BioBank data of more than 440,000 participants.

https://www.theguardian.com/society/2023/nov/29/lower-socioeconomic-status-triples-risk-of-early-onset-dementia

#neuroscience

El Duvelle
3 days ago

The Journal of Neuroscience is moving on to Open (but still anonymous) Peer-reviews! Nice!

Introducing Open Peer Review at JNeurosci

#Neuroscience #PeerReview

Albert Cardona
3 days ago

Loren Looger, legendary protein wrangler, who always generously shared their genetically encoded calcium indicators and more while still in development and unpublished, is asking for labs to co-write grants with him:

"Dear science world, I need help, please. If you like the tools and data we generate, and our shareware attitude, can you please co-apply for funding with us? It turns out that I'm terrible at writing grants, and we need $$ or else we can't make more GCaMPs, RCaMPs, SnFRs (we've branched out to neuromodulators and neuropeptides), FPs, viruses, tags, etc. We'll also make whatever you want, but we need $$ to do it. DM or email me, sooner is better. Sorry to be desperate, but we want to keep doing this, and I'm not sure we can."

https://profiles.ucsd.edu/loren.looger

#neuroscience #GCaMP #RCaMP #SnFR #ProteinEngineering #GECIs

Albert Cardona
3 days ago

The Devineni lab at Emory University is recruiting a research assistant and PhD students, funded by the NIH, to work on #Drosophila #neuroscience:

https://devinenilab.org/join-us

#Fedihire #PhDjobs

Albert Cardona
3 days ago

This Scientific American issue from 1979 reads like a who's who of early neuroscience research:

Cowan, Crick, Kandel, Hubel, Wiesel, Stevens ...

https://www.scientificamerican.com/issue/sa/1979/09-01/

#icanhazpdf ?

In particular, Ordaz et al. 2017 https://doi.org/10.4103%2F1673-5374.213532 credit Francis Crick in this issue as having formulated the need for optical methods with cellular resolution to control the activity of neurons - a precursor to the development of optogenetics.

Crick's idea didn't come out of the blue: by then, bacteriorhodopsins (light-gated ion channels for protons) had been known and published for almost a decade (Oesterhelt and Stoeckenius, 1971 https://www.nature.com/articles/newbio233149a0 ), and halorhodopsin (light-gated chloride channel) had been reported 2 years earlier (Matsuno-Yagi and Mukohata 1977 https://www.sciencedirect.com/science/article/abs/pii/0006291X77912451 ).

(Channelrhodopsin, a light-gated cation channel that can depolarise and therefore activate neurons, wasn't reported until 2002, by Nagel et al. 2002 https://www.science.org/doi/full/10.1126/science.1072068 ).

#neuroscience #optogenetics

Young individuals with autism not only experience heightened daily stress but also tend to employ less effective emotional regulation strategies compared to their non-autistic peers.

https://www.psypost.org/2023/11/autism-and-stress-a-pivotal-study-highlights-unique-emotional-challenges-214781

#neuroscience

Greg Lloyd
3 days ago

Brain Study Suggests Traumatic Memories Are Processed as Present Experience

“The brain doesn’t look like it’s in a state of memory; it looks like it is a state of present experience.”

Indeed, the authors conclude in the paper, “traumatic memories are not experienced as memories as such,” but as “fragments of prior events, subjugating the present moment.”

#Neuroscience

Gift link https://www.nytimes.com/2023/11/30/health/ptsd-memories-brain-trauma.html?unlocked_article_code=1.CU0.T2vR.1KiZ6o5WKbUa&smid=nytcore-ios-share&referringSource=articleShare

Robin Gutzen
3 days ago

Did you ever wish constructing a neural data analysis was more like a choose-your-own-adventure story? 👨‍💻

We just released version 0.1. of the "Collaborative Brain Wave Analysis Pipeline (Cobrawap)" 🐍
https://cobrawap.readthedocs.io

Simply pick and combine reusable method blocks and parameter configurations to build a reproducible #AnalysisWorkflow that is adaptable to heterogenous data sources of cortical wave activity 🌊🧠
#Neuroscience #ResearchSoftware #BrainWaves

Brains
3 days ago

🍿 The second half of #ISPSM's free, international, online conference starts in less than 24 hours! Two more days of #cognitiveScience talks from great scholars all over the world!

Check it out: https://www.neuralmechanisms.org/ispsm-conference.html?fbclid=IwAR2k9OcjKsBFaYHT2nCiEYvYZIumJQger8ciXkE2jY8_kdqCEnmCBf4tMi4

#cognitiveScience #neuroscience #philosophyOfMind #philosophy

Thanks to our co-founder @Gualtiero and our partners at #NeuralMechanisms online for championing accessible and sustainable conferencing!

Silvia Siret
3 days ago

https://vm.tiktok.com/ZGed3eo8y/
Science has been catching up with what Family Constellations facilitators have always been witnessing.
#epigenetics #familyconstellations #neuroscience #inheritedtrauma

Alan Kotok
3 days ago

A developer of medical monitoring systems with data from wearable devices will soon start asking individuals with epilepsy to offer data for an algorithm that predicts seizures.

https://sciencebusiness.technewslit.com/?p=45455

#News #Press #Science #Business #Epilepsy #Seizures #Neuroscience #Wearable #SmartWatch #Algorithm #MachineLearning #ArtificialIntelligence #Forecast #RealWorldData

Earl K. Miller
3 days ago

Hey, that's me.
Earl Miller on How We Think About the Brain
https://ilp.mit.edu/watch/earl-k-miller-profile
#neuroscience

Albert Cardona
3 days ago

@brembs

Institutions seldom if ever dissolve gracefully. More often than not institutions lose their compass, their founders gone, the original purpose forgotten or sidelined, and sustaining its own existence having taken centre place, living another day like zombies.

For #neuroscience, would it be fair to say that #Neuromatch is emerging as a society in the proper sense of the word, and modern -- has its own Mastodon server, for starts; applies technology from the bottom up, and has an online-only open access journal on the works that is both free to read and to publish in.

Brian simulator
3 days ago

We are finally on Mastodon, time for a little #introduction 👋 !

Brian is a #FOSS simulator for biological #SpikingNeuralNetworks, for research in #ComputationalNeuroscience and beyond. It makes it easy to go from a high-level model description in Python, based on mathematical equations and physical units, to a simulation running efficiently on the CPU or GPU.

We have a friendly community and extensive documentation, links to everything on our homepage: https://briansimulator.org

This account will mostly announce news (releases, other notable events), but we're also looking forward to discussing with y'all 💬

#opensource #neuroscience #researchsoftware #introductions

Python code:
from brian2 import *
G = PoissonGroup(100, rates=50*Hz)
M = SpikeMonitor(G)
run(100*ms)
plot(M.t/ms, M.i, '.k');

Below, a raster plot generated by the above code, showing random spiking activity.
Fabrizio Musacchio
3 days ago

Uri Hasson will talk about "#DeepLanguageModels as a #cognitive model for natural #LanguageProcessing in the human brain" 👌

⏰ Dec 7 at 4.15pm CET:
🌍 http://bit.ly/2TPjNZ1

#Neuroscience #deeplearning #CompNeuro

Laurent Perrinet
4 days ago

As a tribute to the beautiful Ouchi Illusion, here is a textured version.

👉 I need your feedback - I personally see the center pulsating, some see colors while fixating the central disk... What is it that you see?

#vision
#neuroscience
#illusion

More examples at
https://laurentperrinet.github.io/sciblog/posts/2023-11-29-ouchi-illusion.html

A textured version of the Ouchi illusion.
Theresa Desrochers
4 days ago

🚨 Job Alert: Deadline Extended to Jan 1 🚨
Need some extra time to apply after SFN/the holiday? We got you. Please share.

Come be my colleague!

The Dept of Neuroscience at Brown University is hiring! A tenure-track Assistant Professor position is available for neuroscientists focusing in any topical area. If you wish to join our inclusive community of dedicated scholars & educators, info & apply @ apply.interfolio.com/132440

#neuroscience #neuro #job #academia

Adult mouse cerebellum with Purkinje neurons labeled in red and axons labeled in green (Image by A. Tulloch, Jaworski laboratory)
The vOICe vision
5 days ago

Why not use The vOICe then? Pans audio from left to right *and* includes visual information of the blind hemifield: The vOICe web app simulating #hemianopia with preserved image-encoding soundscapes in the blind hemifield https://www.seeingwithsound.com/webvoice/webvoice.htm?hemianopiaR&large #BCI #NeuroTech #neuroscience

The vOICe vision
5 days ago

Comparison of uni- and multimodal motion stimulation on visual neglect: A proof-of-concept study https://www.sciencedirect.com/science/article/abs/pii/S0010945223002757 "A new auditory motion stimulation method with music dynamically moving from the right to the left hemispace has recently been shown to improve visual neglect"; #neuroscience

Winston Chiong
6 days ago

We're #hiring! My lab is looking for an assistant clinical research coordinator for #neuroethics research on novel neurotechnology. We're particularly interested in candidates with prior coursework or experience in #neuroscience, #bioethics, and/or #qualitative methods. Please share with anyone who might be interested: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?partnerid=6495&siteid=5861&PageType=JobDetails&jobid=3505283#jobDetails=3505283_5861 #UCSF #ScienceJobs #neurotech #jobs

The vOICe vision
6 days ago

(2015) Use of sensory substitution devices as a model system for investigating cross-modal #neuroplasticity in humans http://dx.doi.org/10.4103/1673-5374.169612 Visual cortex activation by The vOICe and BrainPort sensory substitution devices for the blind. #neuroscience #blindness

Visual cortex activation by The vOICe and BrainPort sensory substitution devices for the blind.
MPI for Biol. Intelligence
6 days ago

📢 Attention Postdocs: Get the chance to visit our institute and present & discuss your research! We invite postdocs in neuroscience, ecology and other fields related to our research to apply for our emerging scientist talk series.

Apply until February 29th: https://www.bi.mpg.de/ess

Art by @somedonkey

#wisskomm #scicomm #science #ScienceMastodon #research #ecology #neuroscience #postdoc #postdocs #talkseries

El Duvelle
1 week ago

#SFN23 poll: did you test positive to #Covid19 either during or after the conference?

(For context: SFN is a #Neuroscience conference with more than 20000 people and very few were masked)

Albert Cardona
1 week ago

@NicoleCRust

And to note that Geerlig's point (1) above on the mismatch between white matter tracts and functional networks should be pondered by those using tractography (another coarse spatial resolution technique) to make models of brain function. There are many such papers.

@tdverstynen

#fMRI #tractography #neuroscience

Albert Cardona
1 week ago

@NicoleCRust

In 2015, I attended the first talk ever featuring fMRI where I found the application and results convincing. The talk was by Linda Geerligs and she described her, at the time, recent paper:

"A brain-wide study of age-related changes in functional connectivity" Geerligs et al. 2015
Cerebral cortex 25 (7):1987-99 https://academic.oup.com/cercor/article/25/7/1987/462366

The work focuses on longitudinal studies on humans, studying the same person over the years with fMRI. In her talk, she pointed out that:

(1) functional networks are not correlated with white matter tracts;
(2) there is a strong decline in functional network modularity with age;
(3) with age; intramodule connectivity decreases and intermodule connectivity increases;
(4) old adults that maintain the highly segregated functional network retain their mental abilities.

Overall I found the technique well suited to the question. In the first place because the study is longitudinal, comparing subjects to themselves over time. In the second place, because it did not attempt to make statements about specific areas of the brain, but rather, on how the relationships between areas, as far as they could be observed, changed over time within an individual.

An interesting study from which what we learn is matched to the strengths and limitations of the technique, and which does not attempt to make sweeping statements about the function of specific areas of the brain. At least that's what Geerligs did in her beautiful talk.

There may be caveats and limitations to the study, but as a non-fMRI specialist, I am unable to see them. Reads humble and as precise as it can be, not more and not less.

@tdverstynen

#neuroscience #fMRI

Albert Cardona
1 week ago

@NicoleCRust

One study that comes to mind is:

"Motor Control by Sensory Cortex" by Matyas et al. 2010 (Carl Petersen's lab) https://www.science.org/doi/full/10.1126/science.1195797

... where they report "an additional and equally direct pathway for cortical motor control driven by the primary somatosensory cortex" in mice. This surprising result, breaking with Penfield's century-old division of labour between the motor cortex and the somatosensory cortex, is supported by voltage-sensitive dye (VSD) imaging of the whole mouse brain, showing widespread activity propagation with latencies of tens of milliseconds across most of the whole brain.

Suppose we were to attempt a similar measurement in humans with fMRI. What would we see with the very low pass filter in the temporal and spatial dimensions that we get from fMRI?

Perhaps this is indeed the wrong question, and in humans we ought to be asking different questions. But what questions? Matyas et al. highlights:

(1) how fast and wide signals spread across the whole mammalian brain;
(2) the inaccuracy of old neuroanatomical divisions of the brain;
(3) the fact that a much larger fraction of the brain is involved in any one behaviour than previously thought, larger than would have been ideal to make sense of the brain as a modular system when its activity is monitored with the low pass filter that is fMRI.

My question is: what kind of studies are sensible given fMRI's strengths and limitations? I have one example in the next post.

ICMS: intracortical microstimulation.

@tdverstynen

#neuroscience #VoltageDyes #mouse #fMRI

Teixi
1 week ago

@albertcardona @mariam

Amazing to find @albertcardona OP cited book:
'Principles of neural science' Kandel et al (yet 5th edition)

Listed in the #neuroscience Basic literature section in @MolemanPeter site:
https://breininactie.com/basic-literature/

Would suggest one for now
https://www.thebsps.org/reviewofbooks/barack-on-bickle-et-al/

Which basic/fundamental #neurobooks would you suggest to add to the list?

https://breininactie.com/basic-literature/

#neurobuzz

Teixi
1 week ago

@DrYohanJohn

#JohnBickle #neurohistory lecture:

#compneuro limits

A Hodgkin & A Huxley
1952s
Papers quartet duo written
—with one B Katz trio

Pioneering voltage-clamp squid neural implant.

First action potentials recordings!

Last paper on how maths calculus derived from experiments datasets.

Thus predictions caveat:
Never link causal mechanisms.

ps: Q&A critical feedback:
Skilled lecturer turns into scientific dialogues!

https://www.youtube.com/watch?v=g85bgHul7Ns

#oldneuropapers
#neuroscience
#neurobuzz

The vOICe vision
1 week ago

Parametric information about eye movements is sent to the ears https://www.pnas.org/doi/10.1073/pnas.2303562120 #neuroscience

(YouTube) Moving eyes make the ears squeak https://www.youtube.com/watch?v=P3geSFX48ig "Scientists can now pinpoint where someone is looking just by listening to their ears"

Your eyes talk to your ears - Scientists know what they're saying https://today.duke.edu/2023/11/your-eyes-talk-your-ears-scientists-know-what-theyre-saying "A new finding that eye movements can be decoded by the sounds they generate in the ear reveals that hearing may be affected by vision"

Surly Amy
1 week ago
Jeroen SZ 🦣
1 week ago

How do we learn? Neuroscientists pinpoint how memories are likely to be stored in the #brain | ScienceDaily

What is the mechanism that allows our brains to incorporate new information about the world, and form memories? New work by a team of neuroscientists shows that learning occurs through the continuous formation of new connectivity patterns between specific engram cells in different regions of the brain

#Memory #Neuroscience

https://www.sciencedaily.com/releases/2023/11/231121175231.htm

Alan Kotok
1 week ago

Researchers from university labs in the U.K. are developing models of brain cell interactions using a company's synthetic human cells derived from stem cells.

https://sciencebusiness.technewslit.com/?p=45434

#News #Press #Science #Business #Biotechnology #Neuroscience #Brain #StemCells #SyntheticBiology #CellBiology #Collaboration #Neurons #Microglia #UK

Albert Cardona
1 week ago

Periodic reminder of what fMRI's BOLD signal is measuring, and its temporal dynamics:

"blood oxygenation level–dependent (BOLD) contrast. [...] increased signal in a voxel measured with an EPI [echo planar imaging] sequence indicates recent neuronal activity because of the relative increase in local blood oxygenation that accompanies such activity. The temporal profile of this BOLD response, known as the hemodynamic response function, looks like a bell curve with a long tail, peaking around 4 to 5 seconds after local neural activity and returning to baseline after 12 to 15 seconds."

From "Principles of Neural Science", Kandel et al. 6th edition, page 115.

No matter how fast the EPI imaging is (~100 ms), the BOLD dynamics makes GCaMP look lighting fast. Temporally deconvolving BOLD is possible, to a point, but remember its spatial resolution is measured in millimetres, whereas neuronal somas measure ~0.025 millimetres.

#fMRI #BOLD #neuroscience

European Research Council (ERC
1 week ago

R to @ERC_Research: Listen to "Drugs, alcohol and social media: The science of the brain" on
▶️ Soundcloud https://bit.ly/47kuZ05
▶️ Spotify https://spoti.fi/47mATOt
▶️ Google Podcasts https://bit.ly/3R7F4I3

@UniofOxford @NeuroBioLtd @baroness_susan #neuroscience

🐦🔗: https://nitter.cz/ERC_Research/status/1727590407897534573#m

[2023-11-23 07:30 UTC]

Albert Cardona
2 weeks ago

These results were reproduced 35 years later by Witvliet et al. 2021:

"The wiring diagram is not stereotyped"

"Each worm has connections that are not found in other individuals.
About 43% of all cell–cell connections—accounting for 16% of all chemical synapses—are not conserved between isogenic individuals. By contrast, physical contacts between neurites at birth are maintained across developmental stages. Wiring variability contrasts with the assumption that the C. elegans connectome is hardwired."

https://www.nature.com/articles/s41586-021-03778-8

#Celegans #neuroscience

Fig. 2 | Connectomes of isogenic individuals include both stereotyped and
variable connections. a, Example of a sensory sub-circuit across maturation.
Circles represent cells, colour-coded by cell type. Lines indicate stable (black),
developmentally dynamic (blue) and variable (grey) connections. b, Total
number of stable, developmentally dynamic and variable connections across
maturation. c, Total number of synapses in stable, developmentally dynamic
and variable connections across maturation. d, Wiring diagram with invariant (stable and developmentally dynamic) connections between different cell types. Connections with statistically significantly different proportions of
developmentally dynamic connections are denoted, *P = 3.2 × 10 −2 (motor–
muscle), 4.2 × 10 −2 (inter–motor), ***P = 2.0 × 10 −5 (inter–inter), two-tailed z-test,
false discovery rate (FDR)-adjusted using Benjamini–Hochberg correction
(n = 160 (interneuron–interneuron), 52 (interneuron–motor neuron) and 145
(motor neuron–muscle) observations).
The vOICe vision
2 weeks ago

Cf. Face shape processing via visual-to-auditory sensory substitution activates regions within the face processing networks in the absence of visual experience https://www.frontiersin.org/articles/10.3389/fnins.2022.921321/full #neuroscience #EyeMusic

The vOICe vision
2 weeks ago

Sound-encoded faces activate the left fusiform face area in the early blind https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0286512 visual-to-auditory sensory substitution, #neuroscience #blindness #PSVA

Vineet Tiruvadi
2 weeks ago

Enjoying this book immensely and feel like I'm finally making cohesive progress in CatT foundations.

This should probably be required reading in every #STEM PhD program.

#science #engineering #medicine #neuroscience

Albert Cardona
2 weeks ago

Little known facts of the #Celegans #connectome :

The original connectome was mapped from 5 different volumes, from 4 hermaphrodites and 1 male.

White et al. 1986 https://royalsocietypublishing.org/doi/10.1098/rstb.1986.0056

Brenner, without skipping a beat, stated this served his purposes just fine: to study variability in synaptic connectivity among otherwise isogenic animals – and found lots, enough to state that genetic determinism w.r.t. neural circuit configuration as understood at the time was largely hogwash.

https://albert.rierol.net/tell/20200419_Sydney_Brenner_and_the_broader_world.html

#neuroscience

APPENDIX 1. CONNECTIVITY DATA
In this section, all the detailed connectivity data for each of the neuron classes are presented. The neuron classes are arranged in alphabetical order; the data for each class are fairly self-contained. Some classes have been grouped together because they share many common features; PLM is listed with ALM, PLN with ALN, PVM with AVM and PQR with AQR.
The data that are presented were derived primarily from three reconstructed animals; the N2T series, the N2U series and the JSE series. Together these series covered the whole of the animal except for a region in the posterior body (figure A 1). This region was covered by a partial reconstruction of a male (N2Y series). Data from this animal provided information on the neurons of the posterior lateral ganglia and the motoneurons of the posterior ventral cord. The neuropile of the nerve ring and anterior ventral cord was also reconstructed from an L4
larva (JSH series, figure A 1). These data were mainly used as a check on the N2U reconstructions, which covered this region and are not shown, except in the case ofRMF, where
there was a significant difference between the two series.

FIGURE A 1. The regions covered by the five separate reconstructions. The N2T, N2U and JSE series were adult
hermaphrodites, the JSH series was an L4 larva and the N2Y series was an adult male.

It was a pleasure to discuss advances in deep brain stimulation, treatment of non-motor symptoms, and other topics in Parkinson's disease with Dr. Michael Okun in this new podcast episode!

https://www.michaeljfox.org/podcast/episode-3-new-frontiers-deep-brain-stimulation-research-parkinsons-disease-dr-michael-okun

#neuroscience #neurology #parkinsonsdisease #research #science #podcast #podcasts #STEM #scicomm #sciencecommunication

This is the cover art image for "The Parkinson's Research Podcast: New Discoveries in Neuroscience". It is a dark blue square, and the title of the show appears on the left side of the image in white. In the bottom left corner, the logo for The Michael J. Fox Foundation is pictured in orange. On the right side, a line-art image of a microscope is depicted in orange.
Yohan John 🤖🧠
2 weeks ago

"... to dematerialize the world ..."

Phrase of the day.

https://doi.org/10.1093/brain/awad389

HT @PessoaBrain

#Neuroscience

The vOICe vision
2 weeks ago

Our brains are not able to 'rewire' themselves, despite what most scientists believe, new study argues https://www.cam.ac.uk/research/news/our-brains-are-not-able-to-rewire-themselves-despite-what-most-scientists-believe-new-study-argues (Functional) 'rerouting' would indeed be a better word. #neuroscience

Earl K. Miller
2 weeks ago

When the conference doors close, these scientists rock out.

A Pavlov’s Dogz show has become tradition at the annual Society for Neuroscience meeting.
https://www.thetransmitter.org/community/when-the-conference-doors-close-these-scientists-rock-out/
#neuroscience

The vOICe vision
2 weeks ago

Against cortical reorganisation https://elifesciences.org/articles/84716 A case against sensory substitution? Does Nature fail to employ POTS-like functional rewiring (functional reorganization) in the brain to learn and adapt? #neuroscience

Earl K. Miller
2 weeks ago
Ben Waber
2 weeks ago

First was an inspiring talk by Edward Chang and Gopala Krishna Anumanchipalli on brain computer interfaces for speech and beyond at UC Berkeley. These real experiments that help people who went through catastrophic brain injury speak again are incredible and give hope for even more advances in the future https://www.youtube.com/watch?v=akSLVQvTVFc (2/10) #neuroscience #HCI

manisha
2 weeks ago

Nanoplastics promote conditions for Parkinson's across various lab models, study shows

"Our study suggests that the emergence of micro and nanoplastics in the environment might represent a new toxin challenge with respect to Parkinson's disease risk and progression," West said. "This is especially concerning given the predicted increase in concentrations of these contaminants in our water and food supplies."

https://medicalxpress.com/news/2023-11-nanoplastics-conditions-parkinson-lab.html

#neuroscience #ParkinsonsDisease #nanoplastics

Peter Moleman
2 weeks ago

"It could be argued that generative AI is one of the most beautiful and important inventions of the century – a 21st-century 'mirror' in which we can see ourselves in a new and revealing light. However, when we look behind the mirror, there is nobody there."
Pezzulo G, Parr T, Cisek P, Clark A, Friston K (2023): Generating meaning: active inference and the scope and limits of passive AI. Trends in Cognitive Sciences DOI: 10.1016/j.tics.2023.10.002
#neuroscience

Peter Moleman
2 weeks ago

This article is about the human brain vs AI, but it is also a great summary of how the brain works if you are not interested in AI.
Pezzulo G, Parr T, Cisek P, Clark A, Friston K (2023): Generating meaning: active inference and the scope and limits of passive AI. Trends in Cognitive Sciences DOI: 10.1016/j.tics.2023.10.002
#neuroscience

Theresa Desrochers
3 weeks ago

So long and thanks for all the science DC! It was a great (and very busy) #SfN23 #SfN2023 #neuroscience

Mick Craig
3 weeks ago

Hello science friends! Can anyone point me towards some resources that I could use learn how to do a de novo genome assembly from long reads (@nanopore)? Mammalian species, no reference genome exists. An equally exciting and daunting task.... Please share #neuroscience #genomics

Theresa Desrochers
3 weeks ago

Looking for a great poster to come see? 👀Come see ours now (Tues afternoon) at UU13 #SfN23 #SfN2023 #neuroscience @katiconen

"Zoom Fatigue": Exhaustion caused by video conferencing proven on a neurophysiological level for the first time - Using EEG and ECG data, researchers were able to prove that video conferences and online education formats lead to greater fatigue than face-to-face alternatives.

https://www.tugraz.at/en/tu-graz/services/news-stories/tu-graz-news/singleview/article/zoom-fatigue-ermuedung-durch-videokonferenzen-erstmals-neurophysiologisch-nachgewiesen

#neuroscience